Research output: Contribution to journal › Review article › peer-review
The Role of Lipids in Implementing Specific Functions in the Central Nervous System. / Galkina, O. V.; Vetrovoy, O. V.; Eschenko, N. D.
In: Russian Journal of Bioorganic Chemistry, Vol. 47, No. 5, 01.09.2021, p. 1004-1013.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - The Role of Lipids in Implementing Specific Functions in the Central Nervous System
AU - Galkina, O. V.
AU - Vetrovoy, O. V.
AU - Eschenko, N. D.
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Abstract—: The review is devoted to the features of lipid composition of the brain and the description of specific functions of lipids in ensuring the activity of the nervous system. Lipids are an extremely heterogeneous group of molecules, which leads to a wide variety of biological functions they perform. Implementing the functions of the central nervous system, including the processes of learning, memory, decision-making, and regulation of the functions of other organs (both direct and mediated by the endocrine glands), is achieved by the great variety of pathways for the release of neurotransmitters and neuromodulators, their reception, and action potential generation and propagation. All this, in turn, is determined by the lipid composition of membranes, the presence of particular fatty acids in the lipid composition, as well as lipid metabolism. This review will focus on the role of lipids in neurons.
AB - Abstract—: The review is devoted to the features of lipid composition of the brain and the description of specific functions of lipids in ensuring the activity of the nervous system. Lipids are an extremely heterogeneous group of molecules, which leads to a wide variety of biological functions they perform. Implementing the functions of the central nervous system, including the processes of learning, memory, decision-making, and regulation of the functions of other organs (both direct and mediated by the endocrine glands), is achieved by the great variety of pathways for the release of neurotransmitters and neuromodulators, their reception, and action potential generation and propagation. All this, in turn, is determined by the lipid composition of membranes, the presence of particular fatty acids in the lipid composition, as well as lipid metabolism. This review will focus on the role of lipids in neurons.
KW - astrocytes
KW - brain
KW - central nervous system
KW - lipid metabolism
KW - lipids
KW - neurons
UR - http://www.scopus.com/inward/record.url?scp=85117564027&partnerID=8YFLogxK
U2 - 10.1134/S1068162021050253
DO - 10.1134/S1068162021050253
M3 - Review article
AN - SCOPUS:85117564027
VL - 47
SP - 1004
EP - 1013
JO - Russian Journal of Bioorganic Chemistry
JF - Russian Journal of Bioorganic Chemistry
SN - 1068-1620
IS - 5
ER -
ID: 104112489