The passive and active elements of the potassium secretion system in the frog skin (Russian). / Bakhteeva, V. T.; Natochin Yu., V.
In: Fiziologicheskii Zhurnal SSSR Imeni I.M. Sechenova, Vol. 61, No. 8, 01.01.1975, p. 1242-1248.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The passive and active elements of the potassium secretion system in the frog skin (Russian)
AU - Bakhteeva, V. T.
AU - Natochin Yu., V.
PY - 1975/1/1
Y1 - 1975/1/1
N2 - A method was evolved for studying potassium and sodium transport without labelled ions in the frog skin. The potassium secretion sharply increased after the nystatin had been added to the solution near the skin surface. Suppression of the apical membrane sodium permeability with amiloride or triamterene did not alter the potassium secretion velocity. The nystatinum increased the potassium and sodium permeability. The blocking agents for sodium channels became ineffective in the presence of nystatin. During the nystatin action on the apical membrane, the work of the Na/K pump does not change in the basal plasmatic membrane, while suppression of the pump with strophantin abolishes the potassium secretion. Therefore, the potassium secretion level depends on the apical membrane potassium permeability and is independent of the sodium transport across this membrane; it is due to potassium inflow into the cell with the aid of Na/K pump of the basal plasmatic membrane.
AB - A method was evolved for studying potassium and sodium transport without labelled ions in the frog skin. The potassium secretion sharply increased after the nystatin had been added to the solution near the skin surface. Suppression of the apical membrane sodium permeability with amiloride or triamterene did not alter the potassium secretion velocity. The nystatinum increased the potassium and sodium permeability. The blocking agents for sodium channels became ineffective in the presence of nystatin. During the nystatin action on the apical membrane, the work of the Na/K pump does not change in the basal plasmatic membrane, while suppression of the pump with strophantin abolishes the potassium secretion. Therefore, the potassium secretion level depends on the apical membrane potassium permeability and is independent of the sodium transport across this membrane; it is due to potassium inflow into the cell with the aid of Na/K pump of the basal plasmatic membrane.
UR - http://www.scopus.com/inward/record.url?scp=0016689138&partnerID=8YFLogxK
M3 - статья
C2 - 1084297
AN - SCOPUS:0016689138
VL - 61
SP - 1242
EP - 1248
JO - РОССИЙСКИЙ ФИЗИОЛОГИЧЕСКИЙ ЖУРНАЛ ИМ. И.М. СЕЧЕНОВА
JF - РОССИЙСКИЙ ФИЗИОЛОГИЧЕСКИЙ ЖУРНАЛ ИМ. И.М. СЕЧЕНОВА
SN - 0869-8139
IS - 8
ER -
ID: 39274624