Twice exceptional children with coexisting special talents in one area and learning disabilities in other areas represent a particular segment of students who require a complex support. Previous studies with such students were done using mostly the method of individual cases analysis and participants were mainly students with high IQ, but without any special talents in other areas. The aim of this study was to test the hypothesis about the positive impact of an experimental educational program that emphasizes the strong sides of the students and the development of targeted educational skills and their level, as well as self-esteem of students. The study involved 30 school age children with a high level of development of visual-spatial abilities. The results show a significant improvement in organizational skills (based on feedback from parents) and in self-esteem of students (based both on the students' self-report and feedback from parents).