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The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells. / Stolbovaya, A. Yu; Smirnov, I. V.; Pinevich, A. A.; Berlina, M. A.; Kozyreva, A. R.; Shashkova, O. A.; Sokolov, D. I.; Selkov, S. A.; Samoilovich, M. P.

In: Cell and Tissue Biology, Vol. 14, No. 1, 01.01.2020.

Research output: Contribution to journal › Article › peer-review

Harvard

Stolbovaya, AY, Smirnov, IV, Pinevich, AA, Berlina, MA, Kozyreva, AR, Shashkova, OA, Sokolov, DI, Selkov, SA & Samoilovich, MP 2020, 'The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells', Cell and Tissue Biology, vol. 14, no. 1. https://doi.org/10.1134/S1990519X20010095

APA

Stolbovaya, A. Y., Smirnov, I. V., Pinevich, A. A., Berlina, M. A., Kozyreva, A. R., Shashkova, O. A., Sokolov, D. I., Selkov, S. A., & Samoilovich, M. P. (2020). The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells. Cell and Tissue Biology, 14(1). https://doi.org/10.1134/S1990519X20010095

Vancouver

Stolbovaya AY, Smirnov IV, Pinevich AA, Berlina MA, Kozyreva AR, Shashkova OA et al. The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells. Cell and Tissue Biology. 2020 Jan 1;14(1). https://doi.org/10.1134/S1990519X20010095

Author

Stolbovaya, A. Yu ; Smirnov, I. V. ; Pinevich, A. A. ; Berlina, M. A. ; Kozyreva, A. R. ; Shashkova, O. A. ; Sokolov, D. I. ; Selkov, S. A. ; Samoilovich, M. P. / The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells. In: Cell and Tissue Biology. 2020 ; Vol. 14, No. 1.

BibTeX

@article{1a33ec61a1514fd28db2e43eb54bf8ea,
title = "The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells",
abstract = "Abstract: The endothelium of blood vessels plays an important role in the regulation of normal and pathological processes occurring in the tissues. Monoclonal antibodies (MAbs) to endoglin (CD105), a marker of endothelial cells, are considered as potential agents to affect the functional characteristics of endothelial cells. Here, we report the ability of MAbs against several epitopes of endoglin to modify the functional characte-ristics of human EA.hy926 endothelial cells in vitro. Different MAbs were found to slow down cell proliferation or migration, to increase the adhesion of monocyte-like cells, or to reduce the rate of soluble endoglin accumulation in a culture medium. Two MAbs of the eight studied reagents were able to affect several functional characteristics of endothelial cells.",
keywords = "adhesion, CD105, cell migration, EA.hy926, endoglin, endothelium, monoclonal antibody, soluble endoglin",
author = "Stolbovaya, {A. Yu} and Smirnov, {I. V.} and Pinevich, {A. A.} and Berlina, {M. A.} and Kozyreva, {A. R.} and Shashkova, {O. A.} and Sokolov, {D. I.} and Selkov, {S. A.} and Samoilovich, {M. P.}",
note = "Publisher Copyright: {\textcopyright} 2020, Pleiades Publishing, Ltd. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = jan,
day = "1",
doi = "10.1134/S1990519X20010095",
language = "English",
volume = "14",
journal = "Cell and Tissue Biology",
issn = "1990-519X",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - The Influence of Monoclonal Antibodies to Human Endoglin on the Functional Characteristics of EA.hy926 Endothelial Cells

AU - Stolbovaya, A. Yu

AU - Smirnov, I. V.

AU - Pinevich, A. A.

AU - Berlina, M. A.

AU - Kozyreva, A. R.

AU - Shashkova, O. A.

AU - Sokolov, D. I.

AU - Selkov, S. A.

AU - Samoilovich, M. P.

N1 - Publisher Copyright: © 2020, Pleiades Publishing, Ltd. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Abstract: The endothelium of blood vessels plays an important role in the regulation of normal and pathological processes occurring in the tissues. Monoclonal antibodies (MAbs) to endoglin (CD105), a marker of endothelial cells, are considered as potential agents to affect the functional characteristics of endothelial cells. Here, we report the ability of MAbs against several epitopes of endoglin to modify the functional characte-ristics of human EA.hy926 endothelial cells in vitro. Different MAbs were found to slow down cell proliferation or migration, to increase the adhesion of monocyte-like cells, or to reduce the rate of soluble endoglin accumulation in a culture medium. Two MAbs of the eight studied reagents were able to affect several functional characteristics of endothelial cells.

AB - Abstract: The endothelium of blood vessels plays an important role in the regulation of normal and pathological processes occurring in the tissues. Monoclonal antibodies (MAbs) to endoglin (CD105), a marker of endothelial cells, are considered as potential agents to affect the functional characteristics of endothelial cells. Here, we report the ability of MAbs against several epitopes of endoglin to modify the functional characte-ristics of human EA.hy926 endothelial cells in vitro. Different MAbs were found to slow down cell proliferation or migration, to increase the adhesion of monocyte-like cells, or to reduce the rate of soluble endoglin accumulation in a culture medium. Two MAbs of the eight studied reagents were able to affect several functional characteristics of endothelial cells.

KW - adhesion

KW - CD105

KW - cell migration

KW - EA.hy926

KW - endoglin

KW - endothelium

KW - monoclonal antibody

KW - soluble endoglin

UR - http://www.scopus.com/inward/record.url?scp=85081306302&partnerID=8YFLogxK

U2 - 10.1134/S1990519X20010095

DO - 10.1134/S1990519X20010095

M3 - Article

AN - SCOPUS:85081306302

VL - 14

JO - Cell and Tissue Biology

JF - Cell and Tissue Biology

SN - 1990-519X

IS - 1

ER -

ID: 76654394