Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
The formation of calcium and magnesium phosphates of the renal stones depending on the composition of the crystallization medium. / Kuz’mina, Mariya A.; Nikolaev, Anton M.; Frank-Kamenetskaya, Olga V.
Processes and Phenomena on the Boundary Between Biogenic and Abiogenic Nature: Conference proceedings. ed. / Olga V. Frank-Kamenetskaya; Dmitry Yu. Vlasov; Elena G. Panova; Sofia N. Lessovaia. Cham : Springer Nature, 2020. p. 107-118 (Lecture Notes in Earth System Sciences).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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TY - CHAP
T1 - The formation of calcium and magnesium phosphates of the renal stones depending on the composition of the crystallization medium
AU - Kuz’mina, Mariya A.
AU - Nikolaev, Anton M.
AU - Frank-Kamenetskaya, Olga V.
N1 - Conference code: VI
PY - 2020
Y1 - 2020
N2 - The study of the phase formation of phosphates in the solutions simulating the normal inorganic composition of human urine was carried out by the precipitation method. All calcium and magnesium phosphates typical for the kidney stones were synthesized: brushite, octacalcium phosphate, hydroxyapatite, struvite and Mg-whitlockite. The regularities of the calcium and magnesium phosphates formation in the crystallization medium of variable composition were found out. The borders of the crystallization areas of the synthesized phases were determined in the axes «initial pH value—main components’ concentration». In general, phosphates crystallization areas are defined by the starting concentrations of the main components, pH value of the crystallization medium and by the presence of the additional ions in the solution. It was shown that crystallization of any calcium phosphate leads to the significant decreasing of the pH value of the crystallization medium. Adding of the inorganic components typical for the human urine into the Ca–PO4 system leads to the moving of the crystallization area borders of the calcium phosphates (brushite, octacalcium phosphate, apatite). Crystallization doesn’t occur in the areas that are characterized by the composition and pH typical for the normal human urine. Increasing amount of the precursors or pH values leads to the start of the phosphate crystallization.
AB - The study of the phase formation of phosphates in the solutions simulating the normal inorganic composition of human urine was carried out by the precipitation method. All calcium and magnesium phosphates typical for the kidney stones were synthesized: brushite, octacalcium phosphate, hydroxyapatite, struvite and Mg-whitlockite. The regularities of the calcium and magnesium phosphates formation in the crystallization medium of variable composition were found out. The borders of the crystallization areas of the synthesized phases were determined in the axes «initial pH value—main components’ concentration». In general, phosphates crystallization areas are defined by the starting concentrations of the main components, pH value of the crystallization medium and by the presence of the additional ions in the solution. It was shown that crystallization of any calcium phosphate leads to the significant decreasing of the pH value of the crystallization medium. Adding of the inorganic components typical for the human urine into the Ca–PO4 system leads to the moving of the crystallization area borders of the calcium phosphates (brushite, octacalcium phosphate, apatite). Crystallization doesn’t occur in the areas that are characterized by the composition and pH typical for the normal human urine. Increasing amount of the precursors or pH values leads to the start of the phosphate crystallization.
KW - Apatite
KW - Biominerals
KW - Brushite
KW - Octacalcium phosphate
KW - Pathogenic crystallization
KW - Phase equilibrium
KW - Precipitation method
KW - Renal stones
KW - Struvite
KW - Whitlockite
UR - http://www.scopus.com/inward/record.url?scp=85072069326&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-21614-6_6
DO - 10.1007/978-3-030-21614-6_6
M3 - Chapter
AN - SCOPUS:85072069326
SN - 9783030216139
T3 - Lecture Notes in Earth System Sciences
SP - 107
EP - 118
BT - Processes and Phenomena on the Boundary Between Biogenic and Abiogenic Nature
A2 - Frank-Kamenetskaya, Olga V.
A2 - Vlasov, Dmitry Yu.
A2 - Panova, Elena G.
A2 - Lessovaia, Sofia N.
PB - Springer Nature
CY - Cham
Y2 - 24 September 2018 through 27 September 2018
ER -
ID: 46331208