Research output: Contribution to journal › Article › peer-review
The effect of chlorpromazine on intracellular Ca2+ concentration in macrophages. / Krutetskaya, Z.I.; Milenina, L.S.; Naumova, A.A.; Butov, S.N.; Antonov, V.G.; Nozdrachev, A.D.
In: Doklady Biochemistry and Biophysics, Vol. 474, No. 1, 2017, p. 162-164.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The effect of chlorpromazine on intracellular Ca2+ concentration in macrophages
AU - Krutetskaya, Z.I.
AU - Milenina, L.S.
AU - Naumova, A.A.
AU - Butov, S.N.
AU - Antonov, V.G.
AU - Nozdrachev, A.D.
N1 - Krutetskaya, Z.I., Milenina, L.S., Naumova, A.A. et al. The effect of chlorpromazine on intracellular Ca2+ concentration in macrophages. Dokl Biochem Biophys 474, 162–164 (2017). https://doi.org/10.1134/S1607672917030036
PY - 2017
Y1 - 2017
N2 - Using Fura-2AM microfluorimetry, it was shown for the first time that neuroleptic chlorpromazine causes intracellular Ca2+ concentration increase in macrophages due to Ca2+ mobilization from intracellular Ca2+ stores and subsequent Ca2+ entry from the external medium. Chlorpromazine-induced Ca2+ entry is inhibited by La3+ and 2-aminoethoxydiphenyl borate and is associated with Ca2+ store depletion.
AB - Using Fura-2AM microfluorimetry, it was shown for the first time that neuroleptic chlorpromazine causes intracellular Ca2+ concentration increase in macrophages due to Ca2+ mobilization from intracellular Ca2+ stores and subsequent Ca2+ entry from the external medium. Chlorpromazine-induced Ca2+ entry is inhibited by La3+ and 2-aminoethoxydiphenyl borate and is associated with Ca2+ store depletion.
U2 - 10.1134/S1607672917030036
DO - 10.1134/S1607672917030036
M3 - Article
VL - 474
SP - 162
EP - 164
JO - Doklady Biochemistry and Biophysics
JF - Doklady Biochemistry and Biophysics
SN - 1607-6729
IS - 1
ER -
ID: 9236725