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The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms. / Korolev, Dmitry; Postnov, Viktor; Aleksandrov, Ilia; Murin, Igor.

In: Biomolecules, Vol. 11, No. 10, 1544, 19.10.2021, p. 1544-1565.

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@article{02ed9b10ed994e098dc5d20a5f8188d9,
title = "The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms",
abstract = "This review presents the main patterns of synthesis for theranostics platforms. We exam-ine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of na-noparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.",
keywords = "therapy; early diagnosis; theranostics; targeted delivery; medicinal chemistry, Early diagnosis, Medicinal chemistry, Targeted delivery, Theranostics, Therapy",
author = "Dmitry Korolev and Viktor Postnov and Ilia Aleksandrov and Igor Murin",
note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Li-censee MDPI, Basel, Switzerland.",
year = "2021",
month = oct,
day = "19",
doi = "10.3390/biom11101544",
language = "English",
volume = "11",
pages = "1544--1565",
journal = "Biomolecules",
issn = "2218-273X",
publisher = "MDPI AG",
number = "10",

}

RIS

TY - JOUR

T1 - The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

AU - Korolev, Dmitry

AU - Postnov, Viktor

AU - Aleksandrov, Ilia

AU - Murin, Igor

N1 - Publisher Copyright: © 2021 by the authors. Li-censee MDPI, Basel, Switzerland.

PY - 2021/10/19

Y1 - 2021/10/19

N2 - This review presents the main patterns of synthesis for theranostics platforms. We exam-ine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of na-noparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.

AB - This review presents the main patterns of synthesis for theranostics platforms. We exam-ine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of na-noparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.

KW - therapy; early diagnosis; theranostics; targeted delivery; medicinal chemistry

KW - Early diagnosis

KW - Medicinal chemistry

KW - Targeted delivery

KW - Theranostics

KW - Therapy

UR - http://www.scopus.com/inward/record.url?scp=85117206986&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/50e551e1-5dff-39b1-97d6-36b96bd20a15/

U2 - 10.3390/biom11101544

DO - 10.3390/biom11101544

M3 - Review article

C2 - 34680176

AN - SCOPUS:85117206986

VL - 11

SP - 1544

EP - 1565

JO - Biomolecules

JF - Biomolecules

SN - 2218-273X

IS - 10

M1 - 1544

ER -

ID: 87636053