Research output: Contribution to journal › Review article › peer-review
The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms. / Korolev, Dmitry; Postnov, Viktor; Aleksandrov, Ilia; Murin, Igor.
In: Biomolecules, Vol. 11, No. 10, 1544, 19.10.2021, p. 1544-1565.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
AU - Korolev, Dmitry
AU - Postnov, Viktor
AU - Aleksandrov, Ilia
AU - Murin, Igor
N1 - Publisher Copyright: © 2021 by the authors. Li-censee MDPI, Basel, Switzerland.
PY - 2021/10/19
Y1 - 2021/10/19
N2 - This review presents the main patterns of synthesis for theranostics platforms. We exam-ine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of na-noparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.
AB - This review presents the main patterns of synthesis for theranostics platforms. We exam-ine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of na-noparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.
KW - therapy; early diagnosis; theranostics; targeted delivery; medicinal chemistry
KW - Early diagnosis
KW - Medicinal chemistry
KW - Targeted delivery
KW - Theranostics
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=85117206986&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/50e551e1-5dff-39b1-97d6-36b96bd20a15/
U2 - 10.3390/biom11101544
DO - 10.3390/biom11101544
M3 - Review article
C2 - 34680176
AN - SCOPUS:85117206986
VL - 11
SP - 1544
EP - 1565
JO - Biomolecules
JF - Biomolecules
SN - 2218-273X
IS - 10
M1 - 1544
ER -
ID: 87636053