The Balance Hypothesis of the Effect of Socially Important Volatile Chemosignals on Reactivity of Chromosome Machinery of Bone Marrow Dividing Cells in the House Mouse Mus musculus

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The Balance Hypothesis of the Effect of Socially Important Volatile Chemosignals on Reactivity of Chromosome Machinery of Bone Marrow Dividing Cells in the House Mouse Mus musculus. / Daev, E. V.; Glinin, T. S.; Dukelskaya, A. V.

In: Journal of Evolutionary Biochemistry and Physiology, Vol. 48, No. 3, 2012, p. 280-286.

Research output: Contribution to journal › Article

BibTeX

@article{9d33f5dea54341c9abcfd091e0c4e9dc,

title = "The Balance Hypothesis of the Effect of Socially Important Volatile Chemosignals on Reactivity of Chromosome Machinery of Bone Marrow Dividing Cells in the House Mouse Mus musculus",

abstract = "Volatile chemosignals released by female CBA mice are shown to affect the chromosome machinery of bone marrow cells in mature syngenic males in different ways depending on the experimental conditions. Chemosignals excreted by solitary adult females decrease the frequency of mitotic disturbances in bone marrow dividing cells of male recipients as compared with the spontaneous level in control animals. At the same time, 2,5-dimethylpyrazine, a pheromone released only by females caged at high densities, increases the frequency of mitotic disturbances. A preliminary 24-h treatment of males with chemosignals excreted by solitary females reduces the effect of a subsequent exposure to 2,5-dimethylpyrazine, however, the frequency of disturbances is still higher than that in the control. The simultaneous exposure to both chemosignals results in complete neutralization of the 2,5-dimethylpyrazine effect, and the frequency of mitotic disturbances does not differ from that observed after the exposure to solitary female c",

keywords = "mouse, chemosignals, pheromones, bone marrow, chromosomal aberrations, mitotic disturbances",

author = "Daev, {E. V.} and Glinin, {T. S.} and Dukelskaya, {A. V.}",

year = "2012",

doi = "10.1134/S0022093012030048",

language = "English",

volume = "48",

pages = "280--286",

journal = "Journal of Evolutionary Biochemistry and Physiology",

issn = "0022-0930",

publisher = "Pleiades Publishing",

number = "3",

}

RIS

TY - JOUR

T1 - The Balance Hypothesis of the Effect of Socially Important Volatile Chemosignals on Reactivity of Chromosome Machinery of Bone Marrow Dividing Cells in the House Mouse Mus musculus

AU - Daev, E. V.

AU - Glinin, T. S.

AU - Dukelskaya, A. V.

PY - 2012

Y1 - 2012

N2 - Volatile chemosignals released by female CBA mice are shown to affect the chromosome machinery of bone marrow cells in mature syngenic males in different ways depending on the experimental conditions. Chemosignals excreted by solitary adult females decrease the frequency of mitotic disturbances in bone marrow dividing cells of male recipients as compared with the spontaneous level in control animals. At the same time, 2,5-dimethylpyrazine, a pheromone released only by females caged at high densities, increases the frequency of mitotic disturbances. A preliminary 24-h treatment of males with chemosignals excreted by solitary females reduces the effect of a subsequent exposure to 2,5-dimethylpyrazine, however, the frequency of disturbances is still higher than that in the control. The simultaneous exposure to both chemosignals results in complete neutralization of the 2,5-dimethylpyrazine effect, and the frequency of mitotic disturbances does not differ from that observed after the exposure to solitary female c

AB - Volatile chemosignals released by female CBA mice are shown to affect the chromosome machinery of bone marrow cells in mature syngenic males in different ways depending on the experimental conditions. Chemosignals excreted by solitary adult females decrease the frequency of mitotic disturbances in bone marrow dividing cells of male recipients as compared with the spontaneous level in control animals. At the same time, 2,5-dimethylpyrazine, a pheromone released only by females caged at high densities, increases the frequency of mitotic disturbances. A preliminary 24-h treatment of males with chemosignals excreted by solitary females reduces the effect of a subsequent exposure to 2,5-dimethylpyrazine, however, the frequency of disturbances is still higher than that in the control. The simultaneous exposure to both chemosignals results in complete neutralization of the 2,5-dimethylpyrazine effect, and the frequency of mitotic disturbances does not differ from that observed after the exposure to solitary female c

KW - mouse

KW - chemosignals

KW - pheromones

KW - bone marrow

KW - chromosomal aberrations

KW - mitotic disturbances

U2 - 10.1134/S0022093012030048

DO - 10.1134/S0022093012030048

M3 - Article

VL - 48

SP - 280

EP - 286

JO - Journal of Evolutionary Biochemistry and Physiology

JF - Journal of Evolutionary Biochemistry and Physiology

SN - 0022-0930

IS - 3

ER -

ID: 5510563