The analysis of the polyamine oxidase genes in the methylotrophic yeast komagataella phaffii

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The analysis of the polyamine oxidase genes in the methylotrophic yeast komagataella phaffii. / Ivanova, Alina V.; Sidorin, Anton V.; Sambuk, Elena V.; Rumyantsev, Andrei M.

In: Ecological Genetics, Vol. 17, No. 4, 2019, p. 47-55.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{c33c3209594a4842a7b982998c6af196,

title = "The analysis of the polyamine oxidase genes in the methylotrophic yeast komagataella phaffii",

abstract = "Polyamines are present in all living cells and regulate a wide range of biological processes. In Saccharomyces cerevisiae the polyamine oxidase Fms1p converts spermine to spermidine and 3-aminopropionaldehyde, which is necessary for the synthesis of pantothenic acid and hypusination. This paper shows that S. cerevisiae FMS1 gene orthologs are present in all major representatives of the Saccharomycotina subdivision, but their copy numbers are different. In the Komagataella phaffii (Pichia pastoris) yeast, two polyamine oxidase genes (KpFMS1 and KpFMS2) were identified, and the regulation of their promoters activity was studied.",

keywords = "Komagataella phaffii, Methylotrophic yeast, Pichia pastoris, Polyamine oxidases",

author = "Ivanova, {Alina V.} and Sidorin, {Anton V.} and Sambuk, {Elena V.} and Rumyantsev, {Andrei M.}",

year = "2019",

doi = "10.17816/ecogen17447-55",

language = "English",

volume = "17",

pages = "47--55",

journal = "ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА",

issn = "1811-0932",

publisher = "Эко-Вектор",

number = "4",

}

RIS

TY - JOUR

T1 - The analysis of the polyamine oxidase genes in the methylotrophic yeast komagataella phaffii

AU - Ivanova, Alina V.

AU - Sidorin, Anton V.

AU - Sambuk, Elena V.

AU - Rumyantsev, Andrei M.

PY - 2019

Y1 - 2019

N2 - Polyamines are present in all living cells and regulate a wide range of biological processes. In Saccharomyces cerevisiae the polyamine oxidase Fms1p converts spermine to spermidine and 3-aminopropionaldehyde, which is necessary for the synthesis of pantothenic acid and hypusination. This paper shows that S. cerevisiae FMS1 gene orthologs are present in all major representatives of the Saccharomycotina subdivision, but their copy numbers are different. In the Komagataella phaffii (Pichia pastoris) yeast, two polyamine oxidase genes (KpFMS1 and KpFMS2) were identified, and the regulation of their promoters activity was studied.

AB - Polyamines are present in all living cells and regulate a wide range of biological processes. In Saccharomyces cerevisiae the polyamine oxidase Fms1p converts spermine to spermidine and 3-aminopropionaldehyde, which is necessary for the synthesis of pantothenic acid and hypusination. This paper shows that S. cerevisiae FMS1 gene orthologs are present in all major representatives of the Saccharomycotina subdivision, but their copy numbers are different. In the Komagataella phaffii (Pichia pastoris) yeast, two polyamine oxidase genes (KpFMS1 and KpFMS2) were identified, and the regulation of their promoters activity was studied.

KW - Komagataella phaffii

KW - Methylotrophic yeast

KW - Pichia pastoris

KW - Polyamine oxidases

UR - http://www.scopus.com/inward/record.url?scp=85078153208&partnerID=8YFLogxK

U2 - 10.17816/ecogen17447-55

DO - 10.17816/ecogen17447-55

M3 - Article

AN - SCOPUS:85078153208

VL - 17

SP - 47

EP - 55

JO - ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА

JF - ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА

SN - 1811-0932

IS - 4

ER -

ID: 70929389