Tetrazoles for biomedicine. / Popova, Elena A.; Trifonov, Rostislav E.; Ostrovskii, Vladimir A.
In: Russian Chemical Reviews, Vol. 88, No. 6, 01.01.2019, p. 644-676.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Tetrazoles for biomedicine
AU - Popova, Elena A.
AU - Trifonov, Rostislav E.
AU - Ostrovskii, Vladimir A.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The tetrazole ring is an important pharmacophoric moiety. It is a structural part of many pharmaceutical drugs, drug candidates (or lead compounds), and various biochemical reagents. This review summarizes data of the last 10-15 years on the use of tetrazoles in biomedicine and the views on the mechanism of their biological action. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophoric moiety are analyzed. Bibliography — 263 references.
AB - The tetrazole ring is an important pharmacophoric moiety. It is a structural part of many pharmaceutical drugs, drug candidates (or lead compounds), and various biochemical reagents. This review summarizes data of the last 10-15 years on the use of tetrazoles in biomedicine and the views on the mechanism of their biological action. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophoric moiety are analyzed. Bibliography — 263 references.
KW - активность
KW - антибактериальный
KW - биомедицина
KW - противовирусный
KW - противовоспалительный
KW - противогрибковый
KW - противолишайный
KW - противоопухолевый
KW - тетразол
KW - фармакофорный
KW - фрагмент
KW - активность
KW - антибактериальный
KW - биомедицина
KW - противовирусный
KW - противовоспалительный
KW - противогрибковый
KW - противолишайный
KW - противоопухолевый
KW - тетразол
KW - фармакофорный
KW - фрагмент
UR - http://www.scopus.com/inward/record.url?scp=85069598788&partnerID=8YFLogxK
U2 - 10.1070/RCR4864
DO - 10.1070/RCR4864
M3 - Article
AN - SCOPUS:85069598788
VL - 88
SP - 644
EP - 676
JO - Russian Chemical Reviews
JF - Russian Chemical Reviews
SN - 0036-021X
IS - 6
ER -
ID: 51239120