DOI

A series of trans-palladium(II) complexes (trans-[PdCl2L2], L = ethyl 5-R-2H-tetrazol-2-ylacetate, 5-R-2H-tetrazol-2-ylacetamides, R = Me, Ph) has been synthesized, and their structure has been proved by 1H and 13C–{1H} NMR and high-resolution mass spectra and X-ray analysis. Antiproliferative activity of the synthesized complexes has been determined, and the mechanism of their interaction with DNA has been studied by UV and CD spectroscopy.

Original languageEnglish
Pages (from-to)2354-2358
Number of pages5
JournalRussian Journal of General Chemistry
Volume88
Issue number11
DOIs
StatePublished - 1 Nov 2018

    Scopus subject areas

  • Chemistry(all)

    Research areas

  • antiproliferative activity, interaction with DNA, tetrazol-2-ylacetic acid derivatives, tetrazole-containing Pd(II) complexes

ID: 51239371