Synthesis and Evaluation of Antibacterial Activity of 1,2,4-Oxadiazole-Containing Biphenylcarboxylic Acids

Research output: Contribution to journal › Article › peer-review

Department of Physical Organic Chemistry

DOI

https://doi.org/10.1134/S1070363220090042
Final published version

M. V. Tarasenko
S. I. Presnukhina
S. V. Baikov
A. A. Shetnev

Abstract: A one-pot method for the synthesis of biphenylcarboxylic acids containing 1,2,4-oxadiazole ring in the NaOH–DMSO system was developed. The results of in vitro experiments showed that the synthesized compounds exhibit antibacterial activity against susceptible strains of E. coli and S. aureus.

Original language	English
Pages (from-to)	1611-1619
Number of pages	9
Journal	Russian Journal of General Chemistry
Volume	90
Issue number	9
DOIs	https://doi.org/10.1134/S1070363220090042
State	Published - 1 Sep 2020

Research areas

amidoximes, antimicrobial activity, basic catalysis, dicarboxylic acid anhydrides, heterocycles, DESIGN, ONE-POT SYNTHESIS, PERIPHERY, OXADIAZOLE CLASS, ANTIBIOTIC-RESISTANCE, COMBINATION, IN-VITRO, DOUBLE-BLIND, INHIBITORS, DERIVATIVES

Scopus subject areas

Chemistry(all)

ID: 70661044