Synthesis and Antibacterial Activity of 5-Aryl-4-[hydroxy(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones

Research output: Contribution to journal › Article › peer-review

Department of Electrochemistry

DOI

https://doi.org/10.1134/S1070363220080083
Final published version

V. L. Gein
M. I. Kazantseva
L. I. Varkentin
T. M. Zamaraeva
A. N. Yankin
E. V. Beletskii
V. V. Novikova

Abstract: The reaction of tryptamine with aromatic aldehydes and 4-chlorobenzoylpyruvic acid methyl ester led to the formation of 5-aryl-4-[hydroxy-(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones. The resulting compounds were tested for antimicrobial activity.

Original language	English
Pages (from-to)	1426-1431
Number of pages	6
Journal	Russian Journal of General Chemistry
Volume	90
Issue number	8
DOIs	https://doi.org/10.1134/S1070363220080083
State	Published - 1 Aug 2020

Research areas

antimicrobial activity, N,N-dimethyltryptamine heterocyclic analogues, pyrrolidine-2,3-dione derivatives, N-dimethyltryptamine heterocyclic analogues, INHIBITORY-ACTIVITY, pyrrolidine-2, 3-dione derivatives, DERIVATIVES, EFFICIENT, N

Scopus subject areas

Chemistry(all)

ID: 70169330