Supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound: Liquid phase microextraction of sulfonamides

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Supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound: Liquid phase microextraction of sulfonamides. / Bogdanova, Polina; Pochivalov, Aleksei ; Vakh, Christina ; Bulatov, Andrey .

In: Talanta, Vol. 216, 120992, 15.08.2020.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{4262a336daeb4a6c8b8c47b17f6fb1dd,

title = "Supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound: Liquid phase microextraction of sulfonamides",

abstract = "A phenomenon of supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound is presented for the first time. A novel supramolecular solvent-based liquid phase microextraction was developed. In an aqueous phase primary amine formed isotropic solution due to formation of amphiphile supramolecular assembly. The phase separation was achieved by a coacervation process. The monoterpenoid phenol (thymol) acted as a coacervation agent and induced spontaneous in situ formation of tiny supramolecular solvent droplets. The applicability of the proposed microextraction procedure was demonstrated for the separation of sulfonamides from biological fluids (human plasma and serum). An obtained composition of supramolecular solvent (1-decylamine, thymol, water) promoted satisfactory extraction of polar analytes from aqueous phase. The calibration graphs were linear over the concentration ranges of 0.06–50 mg L−1 for sulfamethoxazole, sulfamethazine and sulfapyridine. The limit of detection calculated from the blank tests based on 3σ was 0.02 mg L−1 for all analytes. The total analysis time was 15 min.",

keywords = "Supramolecular solvent, Microextraction, Primary amines, Monoterpenoids, Sulfonamides, Biological fluids",

author = "Polina Bogdanova and Aleksei Pochivalov and Christina Vakh and Andrey Bulatov",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2020",

month = aug,

day = "15",

doi = "10.1016/j.talanta.2020.120992",

language = "English",

volume = "216",

journal = "Talanta",

issn = "0039-9140",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound: Liquid phase microextraction of sulfonamides

AU - Bogdanova, Polina

AU - Pochivalov, Aleksei

AU - Vakh, Christina

AU - Bulatov, Andrey

PY - 2020/8/15

Y1 - 2020/8/15

N2 - A phenomenon of supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound is presented for the first time. A novel supramolecular solvent-based liquid phase microextraction was developed. In an aqueous phase primary amine formed isotropic solution due to formation of amphiphile supramolecular assembly. The phase separation was achieved by a coacervation process. The monoterpenoid phenol (thymol) acted as a coacervation agent and induced spontaneous in situ formation of tiny supramolecular solvent droplets. The applicability of the proposed microextraction procedure was demonstrated for the separation of sulfonamides from biological fluids (human plasma and serum). An obtained composition of supramolecular solvent (1-decylamine, thymol, water) promoted satisfactory extraction of polar analytes from aqueous phase. The calibration graphs were linear over the concentration ranges of 0.06–50 mg L−1 for sulfamethoxazole, sulfamethazine and sulfapyridine. The limit of detection calculated from the blank tests based on 3σ was 0.02 mg L−1 for all analytes. The total analysis time was 15 min.

AB - A phenomenon of supramolecular solvents formation in aqueous solutions containing primary amine and monoterpenoid compound is presented for the first time. A novel supramolecular solvent-based liquid phase microextraction was developed. In an aqueous phase primary amine formed isotropic solution due to formation of amphiphile supramolecular assembly. The phase separation was achieved by a coacervation process. The monoterpenoid phenol (thymol) acted as a coacervation agent and induced spontaneous in situ formation of tiny supramolecular solvent droplets. The applicability of the proposed microextraction procedure was demonstrated for the separation of sulfonamides from biological fluids (human plasma and serum). An obtained composition of supramolecular solvent (1-decylamine, thymol, water) promoted satisfactory extraction of polar analytes from aqueous phase. The calibration graphs were linear over the concentration ranges of 0.06–50 mg L−1 for sulfamethoxazole, sulfamethazine and sulfapyridine. The limit of detection calculated from the blank tests based on 3σ was 0.02 mg L−1 for all analytes. The total analysis time was 15 min.

KW - Supramolecular solvent

KW - Microextraction

KW - Primary amines

KW - Monoterpenoids

KW - Sulfonamides

KW - Biological fluids

UR - https://www.sciencedirect.com/science/article/abs/pii/S0039914020302836#!

UR - http://www.scopus.com/inward/record.url?scp=85082687890&partnerID=8YFLogxK

U2 - 10.1016/j.talanta.2020.120992

DO - 10.1016/j.talanta.2020.120992

M3 - Article

VL - 216

JO - Talanta

JF - Talanta

SN - 0039-9140

M1 - 120992

ER -

ID: 70149168