Suppression of non-selected solutions as a possible brain mechanism for ambiguity resolution in the word fragment task completion task

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Suppression of non-selected solutions as a possible brain mechanism for ambiguity resolution in the word fragment task completion task. / Kireev, Maxim; Korotkov, Alexander; Masharipov, Ruslan; Zheltyakova, Maya; Cherednichenko, Denis; Gershkovich, Valeria ; Moroshkina, Nadezhda ; Slioussar, Natalia ; Allakhverdov, Victor ; Chernigovskaya, Tatiana.

In: Scientific Reports, Vol. 12, No. 1, 1829, 12.2022.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{36c7760588a24eb6811af763c0405867,

title = "Suppression of non-selected solutions as a possible brain mechanism for ambiguity resolution in the word fragment task completion task",

abstract = "Brain systems dealing with multiple meanings of ambiguous stimuli are relatively well studied, while the processing of non-selected meanings is less investigated in the neurophysiological literature and provokes controversy between existing theories. It is debated whether these meanings are actively suppressed and, if yes, whether suppression characterizes any task that involves alternative solutions or only those tasks that emphasize semantic processing or the existence of alternatives. The current functional MRI event-related study used a modified version of the word fragment completion task to reveal brain mechanisms involved in implicit processing of the non-selected solutions of ambiguous fragments. The stimuli were pairs of fragmented adjectives and nouns. Noun fragments could have one or two solutions (resulting in two words with unrelated meanings). Adjective fragments had one solution and created contexts strongly suggesting one solution for ambiguous noun fragments. All fragmented nouns were presented twice during the experiment (with two different adjectives). We revealed that ambiguity resolution was associated with a reduced BOLD signal within several regions related to language processing, including the anterior hippocampi and amygdala and posterior lateral temporal cortex. Obtained findings were interpreted as resulting from brain activity inhibition, which underlies a hypothesized mechanism of suppression of non-selected solutions.",

keywords = "Adult, Amygdala/anatomy & histology, Brain Mapping, Comprehension/physiology, Female, Hippocampus/anatomy & histology, Humans, Language, Magnetic Resonance Imaging, Male, Pattern Recognition, Physiological/physiology, Reaction Time/physiology, Semantics, Temporal Lobe/anatomy & histology, Vocabulary, ACTIVATION, COMPREHENSION, CONTEXT, INHIBITION, MEMORY, COMPETITION, RETRIEVAL, PERCEPTION, MEANINGS, SEMANTIC AMBIGUITY",

author = "Maxim Kireev and Alexander Korotkov and Ruslan Masharipov and Maya Zheltyakova and Denis Cherednichenko and Valeria Gershkovich and Nadezhda Moroshkina and Natalia Slioussar and Victor Allakhverdov and Tatiana Chernigovskaya",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s).",

year = "2022",

month = dec,

doi = "10.1038/s41598-022-05646-5",

language = "English",

volume = "12",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

number = "1",

}

RIS

TY - JOUR

T1 - Suppression of non-selected solutions as a possible brain mechanism for ambiguity resolution in the word fragment task completion task

AU - Kireev, Maxim

AU - Korotkov, Alexander

AU - Masharipov, Ruslan

AU - Zheltyakova, Maya

AU - Cherednichenko, Denis

AU - Gershkovich, Valeria

AU - Moroshkina, Nadezhda

AU - Slioussar, Natalia

AU - Allakhverdov, Victor

AU - Chernigovskaya, Tatiana

PY - 2022/12

Y1 - 2022/12

N2 - Brain systems dealing with multiple meanings of ambiguous stimuli are relatively well studied, while the processing of non-selected meanings is less investigated in the neurophysiological literature and provokes controversy between existing theories. It is debated whether these meanings are actively suppressed and, if yes, whether suppression characterizes any task that involves alternative solutions or only those tasks that emphasize semantic processing or the existence of alternatives. The current functional MRI event-related study used a modified version of the word fragment completion task to reveal brain mechanisms involved in implicit processing of the non-selected solutions of ambiguous fragments. The stimuli were pairs of fragmented adjectives and nouns. Noun fragments could have one or two solutions (resulting in two words with unrelated meanings). Adjective fragments had one solution and created contexts strongly suggesting one solution for ambiguous noun fragments. All fragmented nouns were presented twice during the experiment (with two different adjectives). We revealed that ambiguity resolution was associated with a reduced BOLD signal within several regions related to language processing, including the anterior hippocampi and amygdala and posterior lateral temporal cortex. Obtained findings were interpreted as resulting from brain activity inhibition, which underlies a hypothesized mechanism of suppression of non-selected solutions.

AB - Brain systems dealing with multiple meanings of ambiguous stimuli are relatively well studied, while the processing of non-selected meanings is less investigated in the neurophysiological literature and provokes controversy between existing theories. It is debated whether these meanings are actively suppressed and, if yes, whether suppression characterizes any task that involves alternative solutions or only those tasks that emphasize semantic processing or the existence of alternatives. The current functional MRI event-related study used a modified version of the word fragment completion task to reveal brain mechanisms involved in implicit processing of the non-selected solutions of ambiguous fragments. The stimuli were pairs of fragmented adjectives and nouns. Noun fragments could have one or two solutions (resulting in two words with unrelated meanings). Adjective fragments had one solution and created contexts strongly suggesting one solution for ambiguous noun fragments. All fragmented nouns were presented twice during the experiment (with two different adjectives). We revealed that ambiguity resolution was associated with a reduced BOLD signal within several regions related to language processing, including the anterior hippocampi and amygdala and posterior lateral temporal cortex. Obtained findings were interpreted as resulting from brain activity inhibition, which underlies a hypothesized mechanism of suppression of non-selected solutions.

KW - Adult

KW - Amygdala/anatomy & histology

KW - Brain Mapping

KW - Comprehension/physiology

KW - Female

KW - Hippocampus/anatomy & histology

KW - Humans

KW - Language

KW - Magnetic Resonance Imaging

KW - Male

KW - Pattern Recognition, Physiological/physiology

KW - Reaction Time/physiology

KW - Semantics

KW - Temporal Lobe/anatomy & histology

KW - Vocabulary

KW - ACTIVATION

KW - COMPREHENSION

KW - CONTEXT

KW - INHIBITION

KW - MEMORY

KW - COMPETITION

KW - RETRIEVAL

KW - PERCEPTION

KW - MEANINGS

KW - SEMANTIC AMBIGUITY

UR - http://www.scopus.com/inward/record.url?scp=85124059926&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/874d143c-4405-38c3-b9fa-0f7ea8b325cb/

U2 - 10.1038/s41598-022-05646-5

DO - 10.1038/s41598-022-05646-5

M3 - Article

C2 - 35115559

VL - 12

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 1829

ER -

ID: 92287571