Research output: Contribution to journal › Article › peer-review
Study of the Reversible Dissociation of an Interpolyelectrolyte Complex of Chitosan and Sodium Chondroitin Sulfate in a Monosodium Glutamate Solution. / Лезова, Александра Андреевна; Рогожин, Вячеслав Борисович; Лезов, Алексей Андреевич; Цветков, Николай Викторович.
In: Nanobiotechnology Reports, Vol. 20, No. 1, 01.02.2025, p. 52-58.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Study of the Reversible Dissociation of an Interpolyelectrolyte Complex of Chitosan and Sodium Chondroitin Sulfate in a Monosodium Glutamate Solution
AU - Лезова, Александра Андреевна
AU - Рогожин, Вячеслав Борисович
AU - Лезов, Алексей Андреевич
AU - Цветков, Николай Викторович
PY - 2025/2/1
Y1 - 2025/2/1
N2 - Abstract: The anomalous solubility of an interpolyelectrolyte complex (IPEC) of chitosan (CN) and sodium chondroitin sulfate (SCS) in a monosodium glutamate (MSG) solution associated with its dissociation into the initial components is discovered and studied using viscometry, turbidimetry, dynamic light scattering, static light scattering, and gravimetry. It is shown that complete dissociation of the stoichiometric interpolyelectrolyte complex of the said polyelectrolytes can be achieved in a monosodium glutamate solution with an order of magnitude lower ionic strength than in solutions of other salts. The possibility of the reverse formation of the interpolyelectrolyte complex of chitosan and sodium chondroitin sulfate from its decay products as the concentration of monosodium glutamate decreases is revealed. The possible areas of application of this phenomenon are identified, in particular, in medicine.
AB - Abstract: The anomalous solubility of an interpolyelectrolyte complex (IPEC) of chitosan (CN) and sodium chondroitin sulfate (SCS) in a monosodium glutamate (MSG) solution associated with its dissociation into the initial components is discovered and studied using viscometry, turbidimetry, dynamic light scattering, static light scattering, and gravimetry. It is shown that complete dissociation of the stoichiometric interpolyelectrolyte complex of the said polyelectrolytes can be achieved in a monosodium glutamate solution with an order of magnitude lower ionic strength than in solutions of other salts. The possibility of the reverse formation of the interpolyelectrolyte complex of chitosan and sodium chondroitin sulfate from its decay products as the concentration of monosodium glutamate decreases is revealed. The possible areas of application of this phenomenon are identified, in particular, in medicine.
KW - chitosan
KW - dissociation
KW - films
KW - interpolyelectrolyte complex
KW - monosodium glutamate
KW - ophthalmology
KW - polyelectrolyte
KW - sodium chondroitin sulfate
UR - https://www.mendeley.com/catalogue/4c1c2639-2c64-3ffd-8228-d29defbbfba6/
U2 - 10.1134/S2635167624602572
DO - 10.1134/S2635167624602572
M3 - Article
VL - 20
SP - 52
EP - 58
JO - Nanobiotechnology Reports
JF - Nanobiotechnology Reports
SN - 2635-1676
IS - 1
ER -
ID: 137601624