Research output: Contribution to journal › Article › peer-review
Study of DNA complexation with platinum coordination compounds. / Kas'yanenko, N. A.; Abramchuk, S. S.; Blagodatskikh, I. V.; Bogdanov, A. A.; Gallyamov, M. O.; Kononov, A. I.; Kosmotynskaya, Yu V.; Sitnikova, N. L.; Khokhlov, A. R.
In: Polymer Science - Series A, Vol. 45, No. 10, 2003, p. 960-968.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Study of DNA complexation with platinum coordination compounds
AU - Kas'yanenko, N. A.
AU - Abramchuk, S. S.
AU - Blagodatskikh, I. V.
AU - Bogdanov, A. A.
AU - Gallyamov, M. O.
AU - Kononov, A. I.
AU - Kosmotynskaya, Yu V.
AU - Sitnikova, N. L.
AU - Khokhlov, A. R.
N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2003
Y1 - 2003
N2 - Complexes of DNA with cis-diamminedichloroplatinum and trans-diamminedichloroplatinum were studied by low-gradient viscometry, spectrophotometry, luminescence, dynamic light scattering, and fluorescence and atomic force microscopy. It was demonstrated that a DNA molecule decreases in size upon its interaction with platinum coordination compounds. The formation of DNA complexes with cis-diamminedichloroplatinum reduces the luminescence intensity and the constant of ethidium bromide binding with DNA, while in the case of trans-diamminedichloroplatinum, these effects turn out to be somewhat less pronounced.
AB - Complexes of DNA with cis-diamminedichloroplatinum and trans-diamminedichloroplatinum were studied by low-gradient viscometry, spectrophotometry, luminescence, dynamic light scattering, and fluorescence and atomic force microscopy. It was demonstrated that a DNA molecule decreases in size upon its interaction with platinum coordination compounds. The formation of DNA complexes with cis-diamminedichloroplatinum reduces the luminescence intensity and the constant of ethidium bromide binding with DNA, while in the case of trans-diamminedichloroplatinum, these effects turn out to be somewhat less pronounced.
UR - http://www.scopus.com/inward/record.url?scp=0242412233&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/record.url?scp=0345528208&partnerID=8YFLogxK
M3 - Article
VL - 45
SP - 960
EP - 968
JO - Polymer Science - Series A
JF - Polymer Science - Series A
SN - 0965-545X
IS - 10
ER -
ID: 5443742