Structural brain differences in school-age children with residual speech sound errors. / Preston, Jonathan L.; Molfese, Peter J.; Mencl, W. Einar; Frost, Stephen J.; Hoeft, Fumiko; Fulbright, Robert K.; Landi, Nicole; Grigorenko, Elena L.; Seki, Ayumi; Felsenfeld, Susan; Pugh, Kenneth R.
In: Brain and Language, Vol. 128, No. 1, 01.01.2014, p. 25-33.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Structural brain differences in school-age children with residual speech sound errors
AU - Preston, Jonathan L.
AU - Molfese, Peter J.
AU - Mencl, W. Einar
AU - Frost, Stephen J.
AU - Hoeft, Fumiko
AU - Fulbright, Robert K.
AU - Landi, Nicole
AU - Grigorenko, Elena L.
AU - Seki, Ayumi
AU - Felsenfeld, Susan
AU - Pugh, Kenneth R.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The purpose of the study was to identify structural brain differences in school-age children with residual speech sound errors. Voxel based morphometry was used to compare gray and white matter volumes for 23 children with speech sound errors, ages 8;6-11;11, and 54 typically speaking children matched on age, oral language, and IQ. We hypothesized that regions associated with production and perception of speech sounds would differ between groups. Results indicated greater gray matter volumes for the speech sound error group relative to typically speaking controls in bilateral superior temporal gyrus. There was greater white matter volume in the corpus callosum for the speech sound error group, but less white matter volume in right lateral occipital gyrus. Results may indicate delays in neuronal pruning in critical speech regions or differences in the development of networks for speech perception and production.
AB - The purpose of the study was to identify structural brain differences in school-age children with residual speech sound errors. Voxel based morphometry was used to compare gray and white matter volumes for 23 children with speech sound errors, ages 8;6-11;11, and 54 typically speaking children matched on age, oral language, and IQ. We hypothesized that regions associated with production and perception of speech sounds would differ between groups. Results indicated greater gray matter volumes for the speech sound error group relative to typically speaking controls in bilateral superior temporal gyrus. There was greater white matter volume in the corpus callosum for the speech sound error group, but less white matter volume in right lateral occipital gyrus. Results may indicate delays in neuronal pruning in critical speech regions or differences in the development of networks for speech perception and production.
KW - Children
KW - Speech sound disorders
KW - Speech sound errors
KW - Structural MRI
UR - http://www.scopus.com/inward/record.url?scp=84890260610&partnerID=8YFLogxK
U2 - 10.1016/j.bandl.2013.11.001
DO - 10.1016/j.bandl.2013.11.001
M3 - Article
C2 - 24342151
AN - SCOPUS:84890260610
VL - 128
SP - 25
EP - 33
JO - Brain and Language
JF - Brain and Language
SN - 0093-934X
IS - 1
ER -
ID: 62727207