The aim of the work was to make a comparative analysis of results of treatment of patients with varicose esophago-gastric bleeding depending on using the endoscopic technologies--ligation and sclerotherapy. The investigation included 161 patients. The main group consisted of 65 patients treated with using the endoscopic technologies--ligation and sclerotherapy due to emergency indications. The comparison group included 96 patients given conservative treatment with the application of Blackmoor probe. The endoscopic methods of surgery allowed to get arrest of bleeding reliably more often (92.3 vs 67.7%, p < 0.05). The number of patients having recurrent bleedings in the main group was 2.7 times less, the intrahospital lethality--3.4 times less than in the group of comparison (p < 0.05).