Standard

Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions. / Polyanichko, A. M.; Chikhirzhina, E. V.; Andrushchenko, V. V.; Wieser, H.; Vorob'ev, V. I.

In: Biophysics, Vol. 50, No. 5, 2005, p. 710-715.

Research output: Contribution to journal › Article › peer-review

Harvard

Polyanichko, AM, Chikhirzhina, EV, Andrushchenko, VV, Wieser, H & Vorob'ev, VI 2005, 'Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions', Biophysics, vol. 50, no. 5, pp. 710-715.

APA

Polyanichko, A. M., Chikhirzhina, E. V., Andrushchenko, V. V., Wieser, H., & Vorob'ev, V. I. (2005). Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions. Biophysics, 50(5), 710-715.

Vancouver

Polyanichko AM, Chikhirzhina EV, Andrushchenko VV, Wieser H, Vorob'ev VI. Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions. Biophysics. 2005;50(5):710-715.

Author

Polyanichko, A. M. ; Chikhirzhina, E. V. ; Andrushchenko, V. V. ; Wieser, H. ; Vorob'ev, V. I. / Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions. In: Biophysics. 2005 ; Vol. 50, No. 5. pp. 710-715.

BibTeX

@article{b0ae1f865e214e5db2caae2e7549a298,
title = "Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions",
abstract = "Interactions between manganese ions and the DNA molecules were studied by means of UV and IR spectroscopy, as well as electronic and vibrational circular dichroism. It was shown that the process of manganese ion binding can be subdivided into three stages depending on the content of manganese ions. At the first stage, when the content of manganese ions is low, the interaction of the metal ions with DNA phosphates occurs, causing partial screening of their negative charge and stabilization of the double helix. This stage ends when the manganese-to-phosphate ratio reaches 1 ([Mn]/[P] < 1). At the second stage, at 1 < [Mn]/[P] < 6, synchronous binding to phosphate groups and nitrogen bases of DNA is observed. At this stage, one manganese ion can be simultaneously coordinated to the oxygen of the phosphate group and to the neighboring nitrogen base of DNA. At a higher [Mn]/[P] ratio, the destabilization of the double-helix begins and partial breakage of the hydrogen bonds in the base pairs occurs.",
keywords = "Circular dichroism, DNA, Manganese ions, UV/IR spectroscopy",
author = "Polyanichko, {A. M.} and Chikhirzhina, {E. V.} and Andrushchenko, {V. V.} and H. Wieser and Vorob'ev, {V. I.}",
year = "2005",
language = "English",
volume = "50",
pages = "710--715",
journal = "Biophysics (Russian Federation)",
issn = "0006-3509",
publisher = "Springer Nature",
number = "5",

}

RIS

TY - JOUR

T1 - Spectroscopic investigations of the structure of DNA complexes with Mn 2+ in UV and IR regions

AU - Polyanichko, A. M.

AU - Chikhirzhina, E. V.

AU - Andrushchenko, V. V.

AU - Wieser, H.

AU - Vorob'ev, V. I.

PY - 2005

Y1 - 2005

N2 - Interactions between manganese ions and the DNA molecules were studied by means of UV and IR spectroscopy, as well as electronic and vibrational circular dichroism. It was shown that the process of manganese ion binding can be subdivided into three stages depending on the content of manganese ions. At the first stage, when the content of manganese ions is low, the interaction of the metal ions with DNA phosphates occurs, causing partial screening of their negative charge and stabilization of the double helix. This stage ends when the manganese-to-phosphate ratio reaches 1 ([Mn]/[P] < 1). At the second stage, at 1 < [Mn]/[P] < 6, synchronous binding to phosphate groups and nitrogen bases of DNA is observed. At this stage, one manganese ion can be simultaneously coordinated to the oxygen of the phosphate group and to the neighboring nitrogen base of DNA. At a higher [Mn]/[P] ratio, the destabilization of the double-helix begins and partial breakage of the hydrogen bonds in the base pairs occurs.

AB - Interactions between manganese ions and the DNA molecules were studied by means of UV and IR spectroscopy, as well as electronic and vibrational circular dichroism. It was shown that the process of manganese ion binding can be subdivided into three stages depending on the content of manganese ions. At the first stage, when the content of manganese ions is low, the interaction of the metal ions with DNA phosphates occurs, causing partial screening of their negative charge and stabilization of the double helix. This stage ends when the manganese-to-phosphate ratio reaches 1 ([Mn]/[P] < 1). At the second stage, at 1 < [Mn]/[P] < 6, synchronous binding to phosphate groups and nitrogen bases of DNA is observed. At this stage, one manganese ion can be simultaneously coordinated to the oxygen of the phosphate group and to the neighboring nitrogen base of DNA. At a higher [Mn]/[P] ratio, the destabilization of the double-helix begins and partial breakage of the hydrogen bonds in the base pairs occurs.

KW - Circular dichroism

KW - DNA

KW - Manganese ions

KW - UV/IR spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=33750344040&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33750344040

VL - 50

SP - 710

EP - 715

JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

SN - 0006-3509

IS - 5

ER -

ID: 88206021