The ability to perform an exploratory search and retrieval of relevant documents from a large collection of domain-specific documents is an important requirement both in the field of medicine and other areas. In this paper, we present a unsupervised distributional clustering technique called SOPHIA. SOPHIA provides a semantically meaningful visual clustering of the document corpus in conjunction with an intuitive interactive search facility. We assess the effectiveness of SOPHIA's cluster-based information retrieval for the MEDLINE testset collection known as OHSUMED.