This chapter aims to develop a general modell serve as an information support tool for decision making at the corporate, municipal, and regional levels. It encompasses cost-benefit analysis (CBA) in solid waste management by applying a sustainability promoting approach that is explicitly related to monetary measures. A waste managements efficient decision (WAMED) model based on CBA is proposed and developed to evaluate the ecological-economic efficiency of solid waste management schemes. The employment of common business administration methodology tools is featured. A classification of competing waste management models is introduced to facilitate evaluation of the relevance of the previously introduced WAMED model. Suggestions are made for how to combine the previously introduced EUROPE model, based on the equality principle, with the WAMED model to create economic incentives to reduce solid waste management-related emissions. A fictive case study presents the practical application of the proposed CBA based theory to the landfilling concept. It is concluded that the presented methodology reflects an integrated approach to decreasing negative impacts on the environment and on the health of the population, while increasing economic benefits through the implementation of solid waste management projects.