Research output: Contribution to journal › Article › peer-review
Small fiber neuropathy definition, diagnosis and treatment. / Basantsova, Natalia Y. ; Starshinova, Anna A. ; Dori, Amir; Zinchenko, Yulia S. ; Yablonskiy, Piotr K. ; Shoenfeld, Yehuda .
In: Neurological Sciences, Vol. 40, 2019, p. 1343-1350.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Small fiber neuropathy definition, diagnosis and treatment
AU - Basantsova, Natalia Y.
AU - Starshinova, Anna A.
AU - Dori, Amir
AU - Zinchenko, Yulia S.
AU - Yablonskiy, Piotr K.
AU - Shoenfeld, Yehuda
N1 - Basantsova, N.Y., Starshinova, A.A., Dori, A. et al. Small-fiber neuropathy definition, diagnosis, and treatment. Neurol Sci 40, 1343–1350 (2019). https://doi.org/10.1007/s10072-019-03871-x
PY - 2019
Y1 - 2019
N2 - In the last 30 years, improvement of diagnostic methods enabled routine evaluation of small A-delta and C nerve fibers impairment, which results with the clinical condition known as a small-fiber neuropathy (SFN). This syndrome develops as a result of metabolic, toxic, immune-mediated, or genetic factors. The main clinical features include neuropathic pain and autonomic disturbance, which are occasionally disclaimed due to outstanding fatigue, daily performance decline, anxiety, and depression. As clinical, neurological, nerve conduction, and electromyography studies are commonly normal, diagnosis often depends on the finding of decreased intra-epidermal density of nerve fibers, per skin biopsy. This review highlights the etiology, clinical, diagnostic aspects, and SFN treatment.
AB - In the last 30 years, improvement of diagnostic methods enabled routine evaluation of small A-delta and C nerve fibers impairment, which results with the clinical condition known as a small-fiber neuropathy (SFN). This syndrome develops as a result of metabolic, toxic, immune-mediated, or genetic factors. The main clinical features include neuropathic pain and autonomic disturbance, which are occasionally disclaimed due to outstanding fatigue, daily performance decline, anxiety, and depression. As clinical, neurological, nerve conduction, and electromyography studies are commonly normal, diagnosis often depends on the finding of decreased intra-epidermal density of nerve fibers, per skin biopsy. This review highlights the etiology, clinical, diagnostic aspects, and SFN treatment.
KW - Small fiber neuropathy
KW - diagnosis
KW - Sarcoidosis
KW - AUTOIMMUNITY
KW - Small-fiber neuropathy
KW - Neuropathic pain
KW - Autoimmune diseases
KW - sarcoidosis
UR - https://link.springer.com/article/10.1007/s10072-019-03871-x
M3 - Article
VL - 40
SP - 1343
EP - 1350
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
ER -
ID: 37606169