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Sigma-1 receptor antagonist haloperidol attenuates store-dependent Ca2+ entry in macrophages. / Z.I. Krutetskaya, ; L.S. Milenina, ; A.A. Naumova, ; Бутов, Сергей Николаевич; V.G. Antonov, ; A.D. Nozdrachev.

In: Doklady Biochemistry and Biophysics, Vol. 480, No. 1, 2018, p. 162 -165.

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@article{51b086c5657c40499df2cc371914d295,
title = "Sigma-1 receptor antagonist haloperidol attenuates store-dependent Ca2+ entry in macrophages",
abstract = "Using Fura-2AM microfluorimetry, we have shown for the first time that preincubation of macrophages with sigma-1 receptor antagonist haloperidol leads to a significant inhibition of the store-dependent Ca 2+ entry induced by endoplasmic Ca 2+-ATPase inhibitors thapsigargin or cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of the sigma-1 receptor in the regulation of storedependent Ca 2+ entry in macrophages. ",
keywords = "CELLS, LIGANDS, OPERATED CALCIUM-CHANNELS, SECRETION",
author = "{Z.I. Krutetskaya} and {L.S. Milenina} and {A.A. Naumova} and Бутов, {Сергей Николаевич} and {V.G. Antonov} and {A.D. Nozdrachev}",
note = "Krutetskaya, Z.I., Milenina, L.S., Naumova, A.A. et al. Sigma-1 Receptor Antagonist Haloperidol Attenuates Store-Dependent Ca2+ Entry in Macrophages. Dokl Biochem Biophys 480, 162–165 (2018). https://doi.org/10.1134/S1607672918030109",
year = "2018",
doi = "10.1134/S1607672918030109",
language = "English",
volume = "480",
pages = "162 --165",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Sigma-1 receptor antagonist haloperidol attenuates store-dependent Ca2+ entry in macrophages

AU - Z.I. Krutetskaya, null

AU - L.S. Milenina, null

AU - A.A. Naumova, null

AU - Бутов, Сергей Николаевич

AU - V.G. Antonov, null

AU - A.D. Nozdrachev, null

N1 - Krutetskaya, Z.I., Milenina, L.S., Naumova, A.A. et al. Sigma-1 Receptor Antagonist Haloperidol Attenuates Store-Dependent Ca2+ Entry in Macrophages. Dokl Biochem Biophys 480, 162–165 (2018). https://doi.org/10.1134/S1607672918030109

PY - 2018

Y1 - 2018

N2 - Using Fura-2AM microfluorimetry, we have shown for the first time that preincubation of macrophages with sigma-1 receptor antagonist haloperidol leads to a significant inhibition of the store-dependent Ca 2+ entry induced by endoplasmic Ca 2+-ATPase inhibitors thapsigargin or cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of the sigma-1 receptor in the regulation of storedependent Ca 2+ entry in macrophages.

AB - Using Fura-2AM microfluorimetry, we have shown for the first time that preincubation of macrophages with sigma-1 receptor antagonist haloperidol leads to a significant inhibition of the store-dependent Ca 2+ entry induced by endoplasmic Ca 2+-ATPase inhibitors thapsigargin or cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of the sigma-1 receptor in the regulation of storedependent Ca 2+ entry in macrophages.

KW - CELLS

KW - LIGANDS

KW - OPERATED CALCIUM-CHANNELS

KW - SECRETION

UR - http://www.scopus.com/inward/record.url?scp=85050111414&partnerID=8YFLogxK

U2 - 10.1134/S1607672918030109

DO - 10.1134/S1607672918030109

M3 - Article

VL - 480

SP - 162

EP - 165

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 35251981