Research output: Contribution to journal › Article › peer-review
Saccharin guanidination : Via facile three-component "two saccharins-one dialkylcyanamide" integration. / Dubovtsev, Alexey Yu; Ivanov, Daniil M.; Dabranskaya, Uladzislava; Bokach, Nadezhda A.; Kukushkin, Vadim Yu.
In: New Journal of Chemistry, Vol. 43, No. 27, 21.07.2019, p. 10685-10688.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Saccharin guanidination
T2 - Via facile three-component "two saccharins-one dialkylcyanamide" integration
AU - Dubovtsev, Alexey Yu
AU - Ivanov, Daniil M.
AU - Dabranskaya, Uladzislava
AU - Bokach, Nadezhda A.
AU - Kukushkin, Vadim Yu
PY - 2019/7/21
Y1 - 2019/7/21
N2 - Saccharin (SacH) reacts with the dialkylcyanamides NCNR2 (R2 = Me2, Et2, C4H8, C5H10, and C4H8O) to grant the guanidinated saccharin derivatives Sac-C(C6H4-2-SO3-H)NC+(NH2)NR2 (65-91%) generated via three-component integration; this type of reactivity has never been observed before for saccharin or any of the nitrile substrates.
AB - Saccharin (SacH) reacts with the dialkylcyanamides NCNR2 (R2 = Me2, Et2, C4H8, C5H10, and C4H8O) to grant the guanidinated saccharin derivatives Sac-C(C6H4-2-SO3-H)NC+(NH2)NR2 (65-91%) generated via three-component integration; this type of reactivity has never been observed before for saccharin or any of the nitrile substrates.
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UR - http://www.scopus.com/inward/record.url?scp=85068620217&partnerID=8YFLogxK
U2 - 10.1039/c9nj02656h
DO - 10.1039/c9nj02656h
M3 - Article
AN - SCOPUS:85068620217
VL - 43
SP - 10685
EP - 10688
JO - New Journal of Chemistry
JF - New Journal of Chemistry
SN - 1144-0546
IS - 27
ER -
ID: 46033972