Role of Lipids in Regulation of Neuroglial Interactions

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Role of Lipids in Regulation of Neuroglial Interactions. / Galkina, Olga V. ; Vetrovoy, Oleg V. ; Krasovskaya, Irina E. ; Eschenko, Nataliya D. .

In: Biochemistry (Moscow), Vol. 88, No. 3, 01.03.2023, p. 337-352.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{da6b39a5454e4afdae36abd2136c65a9,

title = "Role of Lipids in Regulation of Neuroglial Interactions",

abstract = "Lipids comprise an extremely heterogeneous group of compounds that perform a wide variety of biological functions. Traditional view of lipids as important structural components of the cell and compounds playing a trophic role is currently being supplemented by information on the possible participation of lipids in signaling, not only intracellular, but also intercellular. The review article discusses current data on the role of lipids and their metabolites formed in glial cells (astrocytes, oligodendrocytes, microglia) in communication of these cells with neurons. In addition to metabolic transformations of lipids in each type of glial cells, special attention is paid to the lipid signal molecules (phosphatidic acid, arachidonic acid and its metabolites, cholesterol, etc.) and the possibility of their participation in realization of synaptic plasticity, as well as in other possible mechanisms associated with neuroplasticity. All these new data can significantly expand our knowledge about the regulatory functions of lipids in neuroglial relationships.",

keywords = "central nervous system, brain, synaptic plasticity, neurons, astrocytes, oligodendrocytes, microglia, neuronal-glial interactions, lipids, lipid metabolism",

author = "Galkina, {Olga V.} and Vetrovoy, {Oleg V.} and Krasovskaya, {Irina E.} and Eschenko, {Nataliya D.}",

note = "Galkina, O.V., Vetrovoy, O.V., Krasovskaya, I.E. et al. Role of Lipids in Regulation of Neuroglial Interactions. Biochemistry Moscow 88, 337–352 (2023). https://doi.org/10.1134/S0006297923030045",

year = "2023",

month = mar,

day = "1",

doi = "10.1134/s0006297923030045",

language = "English",

volume = "88",

pages = "337--352",

journal = "Biochemistry (Moscow)",

issn = "0006-2979",

publisher = "МАИК {"}Наука/Интерпериодика{"}",

number = "3",

}

RIS

TY - JOUR

T1 - Role of Lipids in Regulation of Neuroglial Interactions

AU - Galkina, Olga V.

AU - Vetrovoy, Oleg V.

AU - Krasovskaya, Irina E.

AU - Eschenko, Nataliya D.

N1 - Galkina, O.V., Vetrovoy, O.V., Krasovskaya, I.E. et al. Role of Lipids in Regulation of Neuroglial Interactions. Biochemistry Moscow 88, 337–352 (2023). https://doi.org/10.1134/S0006297923030045

PY - 2023/3/1

Y1 - 2023/3/1

N2 - Lipids comprise an extremely heterogeneous group of compounds that perform a wide variety of biological functions. Traditional view of lipids as important structural components of the cell and compounds playing a trophic role is currently being supplemented by information on the possible participation of lipids in signaling, not only intracellular, but also intercellular. The review article discusses current data on the role of lipids and their metabolites formed in glial cells (astrocytes, oligodendrocytes, microglia) in communication of these cells with neurons. In addition to metabolic transformations of lipids in each type of glial cells, special attention is paid to the lipid signal molecules (phosphatidic acid, arachidonic acid and its metabolites, cholesterol, etc.) and the possibility of their participation in realization of synaptic plasticity, as well as in other possible mechanisms associated with neuroplasticity. All these new data can significantly expand our knowledge about the regulatory functions of lipids in neuroglial relationships.

AB - Lipids comprise an extremely heterogeneous group of compounds that perform a wide variety of biological functions. Traditional view of lipids as important structural components of the cell and compounds playing a trophic role is currently being supplemented by information on the possible participation of lipids in signaling, not only intracellular, but also intercellular. The review article discusses current data on the role of lipids and their metabolites formed in glial cells (astrocytes, oligodendrocytes, microglia) in communication of these cells with neurons. In addition to metabolic transformations of lipids in each type of glial cells, special attention is paid to the lipid signal molecules (phosphatidic acid, arachidonic acid and its metabolites, cholesterol, etc.) and the possibility of their participation in realization of synaptic plasticity, as well as in other possible mechanisms associated with neuroplasticity. All these new data can significantly expand our knowledge about the regulatory functions of lipids in neuroglial relationships.

KW - central nervous system

KW - brain

KW - synaptic plasticity

KW - neurons

KW - astrocytes

KW - oligodendrocytes

KW - microglia

KW - neuronal-glial interactions

KW - lipids

KW - lipid metabolism

UR - https://link.springer.com/article/10.1134/s0006297923030045

UR - https://www.mendeley.com/catalogue/c5c6210c-82ad-3a8b-bac2-57465d83f86f/

U2 - 10.1134/s0006297923030045

DO - 10.1134/s0006297923030045

M3 - Article

VL - 88

SP - 337

EP - 352

JO - Biochemistry (Moscow)

JF - Biochemistry (Moscow)

SN - 0006-2979

IS - 3

ER -

ID: 104144518