The investigation included 421 cases of renal cell carcinoma with metastases of different localization. Tumor advancement was assessed by application of general-view imaging, X-ray, computed and magnetic resonance tomography, ultrasound and osteoscintigraphy. Alterations in the lung were registered in 271 patients (64.4%); metastases into bones--244 (57.9%). Tumor dissemination to retroperitoneal lymph nodes was detected in 166, liver--96 and the brain--6 patients.