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@article{4f2db31bc2ec4c7b9c478d51a50b5639,
title = "Rh(II)-catalyzed condensation of 3-diazotetramic acids with nitriles delivers novel druglike 5,6-dihydro-4H-pyrrolo[3,4-d]oxazol-4-ones",
abstract = "Previously reported 3-diazotetramic acids have been successfully involved in Rh(II)-catalyzed condensation with aliphatic and aromatic nitriles delivering compounds bearing a hitherto unexplored polysubstituted fused oxazole scaffold. The latter was found to be somewhat labile to the addition of nucleophiles (water and benzylamine) which leads to oxazole ring opening and may constitute an entry into polysubstituted pyrrolinones after due investigation of scope.",
author = "Кривовичева, {Василиса Сергеевна} and Кантин, {Григорий Павлович} and Дарьин, {Дмитрий Викторович} and Красавин, {Михаил Юрьевич}",
year = "2023",
month = apr,
day = "28",
doi = "10.1016/j.tetlet.2023.154457",
language = "English",
volume = "120",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Rh(II)-catalyzed condensation of 3-diazotetramic acids with nitriles delivers novel druglike 5,6-dihydro-4H-pyrrolo[3,4-d]oxazol-4-ones

AU - Кривовичева, Василиса Сергеевна

AU - Кантин, Григорий Павлович

AU - Дарьин, Дмитрий Викторович

AU - Красавин, Михаил Юрьевич

PY - 2023/4/28

Y1 - 2023/4/28

N2 - Previously reported 3-diazotetramic acids have been successfully involved in Rh(II)-catalyzed condensation with aliphatic and aromatic nitriles delivering compounds bearing a hitherto unexplored polysubstituted fused oxazole scaffold. The latter was found to be somewhat labile to the addition of nucleophiles (water and benzylamine) which leads to oxazole ring opening and may constitute an entry into polysubstituted pyrrolinones after due investigation of scope.

AB - Previously reported 3-diazotetramic acids have been successfully involved in Rh(II)-catalyzed condensation with aliphatic and aromatic nitriles delivering compounds bearing a hitherto unexplored polysubstituted fused oxazole scaffold. The latter was found to be somewhat labile to the addition of nucleophiles (water and benzylamine) which leads to oxazole ring opening and may constitute an entry into polysubstituted pyrrolinones after due investigation of scope.

U2 - 10.1016/j.tetlet.2023.154457

DO - 10.1016/j.tetlet.2023.154457

M3 - Article

VL - 120

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

M1 - 154457

ER -

ID: 113686155