Research output: Contribution to journal › Article › peer-review
Results from a global multicenter registry of 6193 patients to refine endoscopic anatomical enucleation of the prostate (REAP) by evaluating trends and outcomes and nuances of prostate enucleation in a real-world setting. / Gauhar, Vineet; Gómez Sancha, Fernando; Enikeev, Dmitry; Sofer, Mario; Fong, Khi Yung; Rodríguez Socarrás, Moisés; Elterman, Dean; Chiruvella, Mallikarjuna; Bendigeri, Mohammed Taif; Tursunkulov, Azimdjon N; Mahajan, Abhay; Bhatia, Tanuj Paul; Ivanovich, Sorokin Nikolai; Gadzhiev, Nariman; Ying, Lie Kwok; Sarvajit, Biligere; Dellabella, Marco; Petov, Vladislav; Somani, Bhaskar Kumar; Castellani, Daniele; Herrmann, Thomas R W.
In: World Journal of Urology, Vol. 41, No. 11, 11.2023, p. 3033-3040.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Results from a global multicenter registry of 6193 patients to refine endoscopic anatomical enucleation of the prostate (REAP) by evaluating trends and outcomes and nuances of prostate enucleation in a real-world setting
AU - Gauhar, Vineet
AU - Gómez Sancha, Fernando
AU - Enikeev, Dmitry
AU - Sofer, Mario
AU - Fong, Khi Yung
AU - Rodríguez Socarrás, Moisés
AU - Elterman, Dean
AU - Chiruvella, Mallikarjuna
AU - Bendigeri, Mohammed Taif
AU - Tursunkulov, Azimdjon N
AU - Mahajan, Abhay
AU - Bhatia, Tanuj Paul
AU - Ivanovich, Sorokin Nikolai
AU - Gadzhiev, Nariman
AU - Ying, Lie Kwok
AU - Sarvajit, Biligere
AU - Dellabella, Marco
AU - Petov, Vladislav
AU - Somani, Bhaskar Kumar
AU - Castellani, Daniele
AU - Herrmann, Thomas R W
N1 - © 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2023/11
Y1 - 2023/11
N2 - PURPOSE: To collect a multicentric, global database to assess current preferences and outcomes for endoscopic enucleation of the prostate (EEP).METHODS: Endourologists experienced in EEP from across the globe were invited to participate in the creation of this retrospective registry. Surgical procedures were performed between January 2020 and August 2022.INCLUSION CRITERIA: lower urinary tract symptoms not responding to or worsening despite medical therapy and absolute indication for surgery.EXCLUSION CRITERIA: prostate cancer, concomitant lower urinary tract surgery, previous prostate/urethral surgery, pelvic radiotherapy.RESULTS: Ten centers from 7 countries, involving 13 surgeons enrolled 6193 patients. Median age was 68 [62-74] years. 2326 (37.8%) patients had large prostates (> 80 cc). The most popular energy modality was the Holmium laser. The most common technique used for enucleation was the 2-lobe (48.8%). 86.2% of the procedures were performed under spinal anesthesia. Median operation time was 67 [50-95] minutes. Median postoperative catheter time was 2 [1, 3] days. Urinary tract infections were the most reported complications (4.7%) followed by acute urinary retention (4.1%). Post-operative bleeding needing additional intervention was reported in 0.9% of cases. 3 and 12-month follow-up visits showed improvement in symptoms and micturition parameters. Only 8 patients (1.4%) required redo surgery for residual adenoma. Stress urinary incontinence was reported in 53.9% of patients and after 3 months was found to persist in 16.2% of the cohort.CONCLUSION: Our database contributes real-world data to support EEP as a truly well-established global, safe minimally invasive intervention and provides insights for further research.
AB - PURPOSE: To collect a multicentric, global database to assess current preferences and outcomes for endoscopic enucleation of the prostate (EEP).METHODS: Endourologists experienced in EEP from across the globe were invited to participate in the creation of this retrospective registry. Surgical procedures were performed between January 2020 and August 2022.INCLUSION CRITERIA: lower urinary tract symptoms not responding to or worsening despite medical therapy and absolute indication for surgery.EXCLUSION CRITERIA: prostate cancer, concomitant lower urinary tract surgery, previous prostate/urethral surgery, pelvic radiotherapy.RESULTS: Ten centers from 7 countries, involving 13 surgeons enrolled 6193 patients. Median age was 68 [62-74] years. 2326 (37.8%) patients had large prostates (> 80 cc). The most popular energy modality was the Holmium laser. The most common technique used for enucleation was the 2-lobe (48.8%). 86.2% of the procedures were performed under spinal anesthesia. Median operation time was 67 [50-95] minutes. Median postoperative catheter time was 2 [1, 3] days. Urinary tract infections were the most reported complications (4.7%) followed by acute urinary retention (4.1%). Post-operative bleeding needing additional intervention was reported in 0.9% of cases. 3 and 12-month follow-up visits showed improvement in symptoms and micturition parameters. Only 8 patients (1.4%) required redo surgery for residual adenoma. Stress urinary incontinence was reported in 53.9% of patients and after 3 months was found to persist in 16.2% of the cohort.CONCLUSION: Our database contributes real-world data to support EEP as a truly well-established global, safe minimally invasive intervention and provides insights for further research.
KW - Male
KW - Humans
KW - Aged
KW - Prostate
KW - Retrospective Studies
KW - Laser Therapy/methods
KW - Prostatectomy/methods
KW - Transurethral Resection of Prostate/methods
KW - Prostatic Hyperplasia/complications
KW - Lasers, Solid-State/therapeutic use
KW - Treatment Outcome
U2 - doi: 10.1007/s00345-023-04626-2.
DO - doi: 10.1007/s00345-023-04626-2.
M3 - Article
C2 - 37782323
VL - 41
SP - 3033
EP - 3040
JO - World Journal of Urology
JF - World Journal of Urology
SN - 0724-4983
IS - 11
ER -
ID: 116243543