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Recurrent evolution of melanism in South American felids. / Schneider, A.; Henegar, C.; Day, K.; Absher, D.; Napolitano, C.; Silveira, L.; David, V.A.; O'Brien, S.J.; Menotti-Raymond, M.; Barsh, G.S.; Eizirik, E.

In: PLoS Genetics, No. 2, 2015, p. e1004892-.

Research output: Contribution to journal › Article

Harvard

Schneider, A, Henegar, C, Day, K, Absher, D, Napolitano, C, Silveira, L, David, VA, O'Brien, SJ, Menotti-Raymond, M, Barsh, GS & Eizirik, E 2015, 'Recurrent evolution of melanism in South American felids', PLoS Genetics, no. 2, pp. e1004892-. https://doi.org/10.1371/journal.pgen.1004892

APA

Schneider, A., Henegar, C., Day, K., Absher, D., Napolitano, C., Silveira, L., David, V. A., O'Brien, S. J., Menotti-Raymond, M., Barsh, G. S., & Eizirik, E. (2015). Recurrent evolution of melanism in South American felids. PLoS Genetics, (2), e1004892-. https://doi.org/10.1371/journal.pgen.1004892

Vancouver

Schneider A, Henegar C, Day K, Absher D, Napolitano C, Silveira L et al. Recurrent evolution of melanism in South American felids. PLoS Genetics. 2015;(2):e1004892-. https://doi.org/10.1371/journal.pgen.1004892

Author

Schneider, A. ; Henegar, C. ; Day, K. ; Absher, D. ; Napolitano, C. ; Silveira, L. ; David, V.A. ; O'Brien, S.J. ; Menotti-Raymond, M. ; Barsh, G.S. ; Eizirik, E. / Recurrent evolution of melanism in South American felids. In: PLoS Genetics. 2015 ; No. 2. pp. e1004892-.

BibTeX

@article{207d9ae9842a4e81b263cb3f5c2a047e,
title = "Recurrent evolution of melanism in South American felids",
abstract = "Morphological variation in natural populations is a genomic test bed for studying the interface between molecular evolution and population genetics, but some of the most interesting questions involve non-model organisms that lack well annotated reference genomes. Many felid species exhibit polymorphism for melanism but the relative roles played by genetic drift, natural selection, and interspecies hybridization remain uncertain. We identify mutations of Agouti signaling protein (ASIP) or the Melanocortin 1 receptor (MC1R) as independent causes of melanism in three closely related South American species: the pampas cat (Leopardus colocolo), the kodkod (Leopardus guigna), and Geoffroy's cat (Leopardus geoffroyi). To assess population level variation in the regions surrounding the causative mutations we apply genomic resources from the domestic cat to carry out clone-based capture and targeted resequencing of 299 kb and 251 kb segments that contain ASIP and MC1R, respectively, from 54 individuals (13-21 per spec",
author = "A. Schneider and C. Henegar and K. Day and D. Absher and C. Napolitano and L. Silveira and V.A. David and S.J. O'Brien and M. Menotti-Raymond and G.S. Barsh and E. Eizirik",
year = "2015",
doi = "10.1371/journal.pgen.1004892",
language = "English",
pages = "e1004892--",
journal = "PLoS Genetics",
issn = "1553-7390",
publisher = "Public Library of Science",
number = "2",

}

RIS

TY - JOUR

T1 - Recurrent evolution of melanism in South American felids

AU - Schneider, A.

AU - Henegar, C.

AU - Day, K.

AU - Absher, D.

AU - Napolitano, C.

AU - Silveira, L.

AU - David, V.A.

AU - O'Brien, S.J.

AU - Menotti-Raymond, M.

AU - Barsh, G.S.

AU - Eizirik, E.

PY - 2015

Y1 - 2015

N2 - Morphological variation in natural populations is a genomic test bed for studying the interface between molecular evolution and population genetics, but some of the most interesting questions involve non-model organisms that lack well annotated reference genomes. Many felid species exhibit polymorphism for melanism but the relative roles played by genetic drift, natural selection, and interspecies hybridization remain uncertain. We identify mutations of Agouti signaling protein (ASIP) or the Melanocortin 1 receptor (MC1R) as independent causes of melanism in three closely related South American species: the pampas cat (Leopardus colocolo), the kodkod (Leopardus guigna), and Geoffroy's cat (Leopardus geoffroyi). To assess population level variation in the regions surrounding the causative mutations we apply genomic resources from the domestic cat to carry out clone-based capture and targeted resequencing of 299 kb and 251 kb segments that contain ASIP and MC1R, respectively, from 54 individuals (13-21 per spec

AB - Morphological variation in natural populations is a genomic test bed for studying the interface between molecular evolution and population genetics, but some of the most interesting questions involve non-model organisms that lack well annotated reference genomes. Many felid species exhibit polymorphism for melanism but the relative roles played by genetic drift, natural selection, and interspecies hybridization remain uncertain. We identify mutations of Agouti signaling protein (ASIP) or the Melanocortin 1 receptor (MC1R) as independent causes of melanism in three closely related South American species: the pampas cat (Leopardus colocolo), the kodkod (Leopardus guigna), and Geoffroy's cat (Leopardus geoffroyi). To assess population level variation in the regions surrounding the causative mutations we apply genomic resources from the domestic cat to carry out clone-based capture and targeted resequencing of 299 kb and 251 kb segments that contain ASIP and MC1R, respectively, from 54 individuals (13-21 per spec

U2 - 10.1371/journal.pgen.1004892

DO - 10.1371/journal.pgen.1004892

M3 - Article

SP - e1004892-

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 2

ER -

ID: 4012047