The characteristics of projects in the nanotechnology industry are considered from the viewpoint of resource provision and conditions of realization, and the specifics of project management problems in the nanotechnology industry are shown. The advantages and disadvantages of the most widespread project man- agement methods are shown, and the possibilities of their application to project management problems in the subject area are evaluated. A project simulation approach based on the use of temporal logic tools is proposed. The advisability of developing branching point-interval time methods for the simulation of nanotechnology projects is substantiated.