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Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases. / Trulioff, Andrey; Ermakov, Alexander; Malashichev, Yegor.

In: Genes, Vol. 8, No. 2, 2017, p. 48.

Research output: Contribution to journal › Literature review

Harvard

Trulioff, A, Ermakov, A & Malashichev, Y 2017, 'Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases', Genes, vol. 8, no. 2, pp. 48. https://doi.org/10.3390/genes8020048

APA

Trulioff, A., Ermakov, A., & Malashichev, Y. (2017). Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases. Genes, 8(2), 48. https://doi.org/10.3390/genes8020048

Vancouver

Trulioff A, Ermakov A, Malashichev Y. Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases. Genes. 2017;8(2):48. https://doi.org/10.3390/genes8020048

Author

Trulioff, Andrey ; Ermakov, Alexander ; Malashichev, Yegor. / Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases. In: Genes. 2017 ; Vol. 8, No. 2. pp. 48.

BibTeX

@article{988c753f0c0b47ddaa82043b38d6b03a,
title = "Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases",
abstract = "Cilia have multiple functions in the development of the entire organism, and participate in the development and functioning of the central nervous system. In the last decade, studies have shown that they are implicated in the development of the visceral left-right asymmetry in different vertebrates. At the same time, some neuropsychiatric disorders, such as schizophrenia, autism, bipolar disorder, and dyslexia, are known to be associated with lateralization failure. In this review, we consider possible links in the mechanisms of determination of visceral asymmetry and brain lateralization, through cilia. We review the functions of seven genes associated with both cilia, and with neurodevelopmental diseases, keeping in mind their possible role in the establishment of the left-right brain asymmetry.",
keywords = "schizophrenia, centrosome, left-right asymmetry, Disc1, PCM-1, pericentrin, abelson helper integrator 1, hamartin, DCDC2, Dyx1c1",
author = "Andrey Trulioff and Alexander Ermakov and Yegor Malashichev",
year = "2017",
doi = "10.3390/genes8020048",
language = "English",
volume = "8",
pages = "48",
journal = "Genes",
issn = "2073-4425",
publisher = "MDPI AG",
number = "2",

}

RIS

TY - JOUR

T1 - Primary Cilia as a Possible Link between Left-Right Asymmetry and Neurodevelopmental Diseases

AU - Trulioff, Andrey

AU - Ermakov, Alexander

AU - Malashichev, Yegor

PY - 2017

Y1 - 2017

N2 - Cilia have multiple functions in the development of the entire organism, and participate in the development and functioning of the central nervous system. In the last decade, studies have shown that they are implicated in the development of the visceral left-right asymmetry in different vertebrates. At the same time, some neuropsychiatric disorders, such as schizophrenia, autism, bipolar disorder, and dyslexia, are known to be associated with lateralization failure. In this review, we consider possible links in the mechanisms of determination of visceral asymmetry and brain lateralization, through cilia. We review the functions of seven genes associated with both cilia, and with neurodevelopmental diseases, keeping in mind their possible role in the establishment of the left-right brain asymmetry.

AB - Cilia have multiple functions in the development of the entire organism, and participate in the development and functioning of the central nervous system. In the last decade, studies have shown that they are implicated in the development of the visceral left-right asymmetry in different vertebrates. At the same time, some neuropsychiatric disorders, such as schizophrenia, autism, bipolar disorder, and dyslexia, are known to be associated with lateralization failure. In this review, we consider possible links in the mechanisms of determination of visceral asymmetry and brain lateralization, through cilia. We review the functions of seven genes associated with both cilia, and with neurodevelopmental diseases, keeping in mind their possible role in the establishment of the left-right brain asymmetry.

KW - schizophrenia

KW - centrosome

KW - left-right asymmetry

KW - Disc1

KW - PCM-1

KW - pericentrin

KW - abelson helper integrator 1

KW - hamartin

KW - DCDC2

KW - Dyx1c1

U2 - 10.3390/genes8020048

DO - 10.3390/genes8020048

M3 - Literature review

VL - 8

SP - 48

JO - Genes

JF - Genes

SN - 2073-4425

IS - 2

ER -

ID: 7734334