Research output: Contribution to journal › Article › peer-review
Positron emission tomography in the diagnosis of recurrent growth of brain tumors. / Skvortsova, T. I.; Brodskaia, Z. L.; Rudas, M. S.; Mozhaev, S. V.; Gurchin, A. F.; Medvedev, S. V.
In: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, No. 2, 01.04.2005, p. 3-7; discussion 7.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Positron emission tomography in the diagnosis of recurrent growth of brain tumors
AU - Skvortsova, T. I.
AU - Brodskaia, Z. L.
AU - Rudas, M. S.
AU - Mozhaev, S. V.
AU - Gurchin, A. F.
AU - Medvedev, S. V.
PY - 2005/4/1
Y1 - 2005/4/1
N2 - The authors analyzed the results of 11C-methionine positron emission tomography (PET) in 101 patients with suspected recurrent brain tumor. The diagnosis was confirmed in 72 patients. The increased 11C-methionine uptake in the initial tumor area is considered to be a crucial PET evidence of a recurrent tumor. On the other hand, brain tissue histological changes associated with surgery, radiation, and chemotherapy were characterized by the low uptake of the tracer. The sensitivity and specificity of PET scanning in detecting tumor recurrence were found to be 95.8 and 96.5%, respectively. 11C-methionine PET is proposed as a reliable technique for early differentiating between a recurrent brain tumor and treatment-induced nonneoplastic changes.
AB - The authors analyzed the results of 11C-methionine positron emission tomography (PET) in 101 patients with suspected recurrent brain tumor. The diagnosis was confirmed in 72 patients. The increased 11C-methionine uptake in the initial tumor area is considered to be a crucial PET evidence of a recurrent tumor. On the other hand, brain tissue histological changes associated with surgery, radiation, and chemotherapy were characterized by the low uptake of the tracer. The sensitivity and specificity of PET scanning in detecting tumor recurrence were found to be 95.8 and 96.5%, respectively. 11C-methionine PET is proposed as a reliable technique for early differentiating between a recurrent brain tumor and treatment-induced nonneoplastic changes.
UR - http://www.scopus.com/inward/record.url?scp=25144512089&partnerID=8YFLogxK
M3 - статья
C2 - 16078626
AN - SCOPUS:25144512089
SP - 3-7; discussion 7
JO - ЖУРНАЛ ВОПРОСЫ НЕЙРОХИРУРГИИ ИМ. Н.Н. БУРДЕНКО
JF - ЖУРНАЛ ВОПРОСЫ НЕЙРОХИРУРГИИ ИМ. Н.Н. БУРДЕНКО
SN - 0042-8817
IS - 2
ER -
ID: 51523863