Research output: Contribution to journal › Article › peer-review
PlasmidSPAdes: Assembling plasmids from whole genome sequencing data. / Antipov, D.; Hartwick, N.; Shen, M.; Raiko, M.; Lapidus, A.; Pevzner, P. A.
In: Bioinformatics, Vol. 32, No. 22, 15.11.2016, p. 3380-3387.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - PlasmidSPAdes: Assembling plasmids from whole genome sequencing data
AU - Antipov, D.
AU - Hartwick, N.
AU - Shen, M.
AU - Raiko, M.
AU - Lapidus, A.
AU - Pevzner, P. A.
PY - 2016/11/15
Y1 - 2016/11/15
N2 - Motivation: Plasmids are stably maintained extra-chromosomal ge- netic elements that replicate independently from the host cell’s chro- mosomes. Although plasmids harbor biomedically important genes, (such as genes involved in virulence and antibiotics resistance), there is a shortage of specialized software tools for extracting and assembling plasmid data from whole genome sequencing projects. Results:We present the plasmidSPAdes algorithm and software tool for assembling plasmids from whole genome sequencing data and benchmark its performance on a diverse set of bacterial genomes
AB - Motivation: Plasmids are stably maintained extra-chromosomal ge- netic elements that replicate independently from the host cell’s chro- mosomes. Although plasmids harbor biomedically important genes, (such as genes involved in virulence and antibiotics resistance), there is a shortage of specialized software tools for extracting and assembling plasmid data from whole genome sequencing projects. Results:We present the plasmidSPAdes algorithm and software tool for assembling plasmids from whole genome sequencing data and benchmark its performance on a diverse set of bacterial genomes
UR - http://www.mendeley.com/research/plasmidspades-assembling-plasmids-whole-genome-sequencing-data
U2 - 10.1093/bioinformatics/btw493
DO - 10.1093/bioinformatics/btw493
M3 - Article
C2 - 27466620
VL - 32
SP - 3380
EP - 3387
JO - Bioinformatics
JF - Bioinformatics
SN - 1367-4803
IS - 22
ER -
ID: 7608307