The paper is devoted to such an important problem of piloted aircraft control as an unfavorable aircraft-pilot coupling. Mainly, the so-called Pilot-Induced Oscillations, i.e., long uncontrolled irregular oscillations which may happen due to the controlling surface magnitude and rate limitations when pilot attempts to control the aircraft with the high rate and accuracy. The simulation and in-flight test results of several PIO events are described, and the literature overview of the PIO prevention method is given.