Low-temperature luminescence spectra of Cu2O crystals grown by different methods (copper oxidation, induction charge melting, magnetron sputtering, and hydrothermal), as well as natural crystals, have been compared. It is suggested that the high quality of natural crystals and crystals grown by the hydrothermal method is due to the fact that they grow for a long time at relatively low temperatures, which facilitates the minimization of stress.