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Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression. / Aksenova, A. Yu; Burdaeva, Ya V.; Radchenko, E. A.; Mironova, L. N.

In: Russian Journal of Genetics, Vol. 44, No. 2, 02.2008, p. 143-149.

Research output: Contribution to journal › Article › peer-review

Harvard

Aksenova, AY, Burdaeva, YV, Radchenko, EA & Mironova, LN 2008, 'Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression', Russian Journal of Genetics, vol. 44, no. 2, pp. 143-149. https://doi.org/10.1134/s102279540802004x

APA

Aksenova, A. Y., Burdaeva, Y. V., Radchenko, E. A., & Mironova, L. N. (2008). Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression. Russian Journal of Genetics, 44(2), 143-149. https://doi.org/10.1134/s102279540802004x

Vancouver

Aksenova AY, Burdaeva YV, Radchenko EA, Mironova LN. Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression. Russian Journal of Genetics. 2008 Feb;44(2):143-149. https://doi.org/10.1134/s102279540802004x

Author

Aksenova, A. Yu ; Burdaeva, Ya V. ; Radchenko, E. A. ; Mironova, L. N. / Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression. In: Russian Journal of Genetics. 2008 ; Vol. 44, No. 2. pp. 143-149.

BibTeX

@article{541f4a674fdc41ec8c083b9fa38bbac4,
title = "Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression",
abstract = "The phenomenon of nonsense suppression, which leads to the stop codons reading-through, may be related to disturbances in the operation of various components of the translation apparatus and the proteins interacting with them. The phosphatase Ppzlp is one of the factors affecting the nonsense suppression efficiency in Saccharomyces yeast. In this work, the impact of the overexpression of gene PPZ1 and its mutant allele PPZ1-R451L on the phenotypic expression of various mutant alleles of genes SUP35 and SUP45 or the yeast prion [PSI +] was analyzed. On the basis of the data obtained, a suggestion about the possible role of proteins Sup35p and Sup45p in the processes mediating the influence of gene PPZ1 overexpression on the efficiency of nonsense suppression is made.",
author = "Aksenova, {A. Yu} and Burdaeva, {Ya V.} and Radchenko, {E. A.} and Mironova, {L. N.}",
note = "Funding Information: ACKNOWLEDGMENTS We are grateful to S.E. Moskalenko, K.V. Volkov, and J. Arino for kindly providing us with plasmids. This work was supported by the Russian Foundation for Basic Research, project nos. 05-04-48 703 and 07-04-00 605.",
year = "2008",
month = feb,
doi = "10.1134/s102279540802004x",
language = "English",
volume = "44",
pages = "143--149",
journal = "Russian Journal of Genetics",
issn = "1022-7954",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "2",

}

RIS

TY - JOUR

T1 - Overexpression of gene PPZ1 in the yeast Saccharomyces cerevisiae affects the efficiency of nonsense suppression

AU - Aksenova, A. Yu

AU - Burdaeva, Ya V.

AU - Radchenko, E. A.

AU - Mironova, L. N.

N1 - Funding Information: ACKNOWLEDGMENTS We are grateful to S.E. Moskalenko, K.V. Volkov, and J. Arino for kindly providing us with plasmids. This work was supported by the Russian Foundation for Basic Research, project nos. 05-04-48 703 and 07-04-00 605.

PY - 2008/2

Y1 - 2008/2

N2 - The phenomenon of nonsense suppression, which leads to the stop codons reading-through, may be related to disturbances in the operation of various components of the translation apparatus and the proteins interacting with them. The phosphatase Ppzlp is one of the factors affecting the nonsense suppression efficiency in Saccharomyces yeast. In this work, the impact of the overexpression of gene PPZ1 and its mutant allele PPZ1-R451L on the phenotypic expression of various mutant alleles of genes SUP35 and SUP45 or the yeast prion [PSI +] was analyzed. On the basis of the data obtained, a suggestion about the possible role of proteins Sup35p and Sup45p in the processes mediating the influence of gene PPZ1 overexpression on the efficiency of nonsense suppression is made.

AB - The phenomenon of nonsense suppression, which leads to the stop codons reading-through, may be related to disturbances in the operation of various components of the translation apparatus and the proteins interacting with them. The phosphatase Ppzlp is one of the factors affecting the nonsense suppression efficiency in Saccharomyces yeast. In this work, the impact of the overexpression of gene PPZ1 and its mutant allele PPZ1-R451L on the phenotypic expression of various mutant alleles of genes SUP35 and SUP45 or the yeast prion [PSI +] was analyzed. On the basis of the data obtained, a suggestion about the possible role of proteins Sup35p and Sup45p in the processes mediating the influence of gene PPZ1 overexpression on the efficiency of nonsense suppression is made.

UR - http://www.scopus.com/inward/record.url?scp=40749147713&partnerID=8YFLogxK

U2 - 10.1134/s102279540802004x

DO - 10.1134/s102279540802004x

M3 - Article

AN - SCOPUS:40749147713

VL - 44

SP - 143

EP - 149

JO - Russian Journal of Genetics

JF - Russian Journal of Genetics

SN - 1022-7954

IS - 2

ER -

ID: 89191185