Methyl 2-diazo-3-oxopropionates were obtained by in situ methoxycarbonylation of methyl ketones followed by diazo transfer onto active methylene group of the intermediate beta-oxo esters. At the second stage, 'sulfonyl-azide-free' (SAFE) diazo transfer protocol in aqueous medium was employed.

Original languageEnglish
Pages (from-to)311-312
Number of pages2
JournalMendeleev Communications
Volume30
Issue number3
Early online date6 Jun 2020
DOIs
StatePublished - 2020

    Scopus subject areas

  • Chemistry(all)

    Research areas

  • diazo transfer, insertion reactions, methoxycarbonylation, SAFE cocktail, β-oxopropionates, KETONES, beta-oxopropionates, PROTOCOL

ID: 59755965