The question concerning the uniqueness of the solution to the problem of the acoustic diffraction by an immersed and isolated thin infinite plate with a finite scatterer is studied. It is shown that, to provide the uniqueness of the solution, the conditions at the scatterer must lead to an energy inequality for a source-free field, which determines the absence of the energy-carrying field components at infinity. A formula that generalizes the Sommerfeld formula is obtained and is used to prove the uniqueness of the solution to the problem of diffraction by a plate immersed in an acoustic medium. For the problem of diffraction of a flexural wave by an irregularity of the plate, the uniqueness theorem is proved only for the case of a fixed or hinged edge. When boundary conditions of a general form are imposed on the scatterer in an isolated plate, the uniqueness of the solution is generally lost, which is also corroborated by an example.