At the beginning of the 21^st century, the multidimensional problems of studying human and society have gone beyond separate sciences. As a result, the need for measuring properties (with providing measurement result traceability), which were considered immeasurable before, has increased. By performing cross-disciplinary and interdisciplinary investigations, to meet this requirement has become possible. In recent years, such investigations have received increased attention at the IMEKO congresses and symposia as well as other international congresses and conferences devoted to measurement science. Interaction in a creative team that consists of professionals in various scientific fields, development of common databases, work in the Internet on joint documents, etc. result in new problems. Organization difficulties concerning such investigations, capacities for overcoming them as well as the efficiency and features of collaborative work in a creative team, have been shown using the example of the experience obtained at the D.I. Mendeleyev Institute for Metrology.