Research output: Contribution to journal › Article › peer-review
Novel brominated fungicidal alkaloid isolated from the marine bryozoan Chartella membranaceatruncata (Smitt, 1868). / Maltseva, A.L.; Kotenko, O.N.; Shabalin, K.A.; Shavarda, A.L.; Winson, M.K.; Ostrovsky, A.N.
In: Studi trentini di scienze naturali, Vol. 94, 2014, p. 163-168.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Novel brominated fungicidal alkaloid isolated from the marine bryozoan Chartella membranaceatruncata (Smitt, 1868)
AU - Maltseva, A.L.
AU - Kotenko, O.N.
AU - Shabalin, K.A.
AU - Shavarda, A.L.
AU - Winson, M.K.
AU - Ostrovsky, A.N.
PY - 2014
Y1 - 2014
N2 - The bryozoan cheilostomatous species Chartella (Terminoflustra) membranaceatruncata was investigated for the presence of antimicrobial agents. Antimicrobial activity against fungi, Gram positive and Gram negative bacteria was detected in an acidic extract of the bryozoan colonies. The strongest antimicrobial activity was seen against the fungal strains Candida albicans and Saccharomyces cereviseae. A combination of electrophoresis and HPLC fractionation methods was used to isolate a fungicidal substance with MW 396.83 Da. The molecular structure was determined using nuclear magnetic resonance analysis and identified as 2-(2,5,8-tribromo-1H-indol-3-yl)ethanamine). Similar tribrominated compounds have been described previously in the ctenostomatous bryozoan species Zoobotryon and Amathia.
AB - The bryozoan cheilostomatous species Chartella (Terminoflustra) membranaceatruncata was investigated for the presence of antimicrobial agents. Antimicrobial activity against fungi, Gram positive and Gram negative bacteria was detected in an acidic extract of the bryozoan colonies. The strongest antimicrobial activity was seen against the fungal strains Candida albicans and Saccharomyces cereviseae. A combination of electrophoresis and HPLC fractionation methods was used to isolate a fungicidal substance with MW 396.83 Da. The molecular structure was determined using nuclear magnetic resonance analysis and identified as 2-(2,5,8-tribromo-1H-indol-3-yl)ethanamine). Similar tribrominated compounds have been described previously in the ctenostomatous bryozoan species Zoobotryon and Amathia.
KW - Chartella
KW - antimicrobial activity
KW - alkaloids
M3 - Article
VL - 94
SP - 163
EP - 168
JO - Studi trentini di scienze naturali
JF - Studi trentini di scienze naturali
SN - 2035-7699
ER -
ID: 5664724