New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

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New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS. / Чучина, Виктория Александровна ; Губаль, Анна Романовна ; Лялькин, Егор Алексеевич ; Соловьев, Николай Дмитриевич; Иваненко, Н.Б.; Ганеев, А.А.

In: Atomic Spectroscopy, Vol. 42, No. 3, 05.2021, p. 120-127.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{63f0822da6614057a50fdba593e298ac,

title = "New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS",

abstract = "A recent trend in glow discharge analysis, previously considered as a {\textquoteleft}purely inorganic{\textquoteright} technique, is related to the effective ionisation of volatile organic compounds (VOCs). This approach was demonstrated to be capable of analysing VOCs in both model gas mixtures and ambient air. In the current study, the possibility of the direct determination of VOCs of different classes of organic compounds (including toluene, p-xylene, chlorobenzene and 1,2,4-trimethylbenzene) in ambient air using microsecond pulsed glow discharge time-of-flight mass spectrometry (µs-Pulsed GD TOFMS) with copper hollow cathode was demonstrated. The ionisation processes with the formation of molecular ions M +, which can be used for quantification, were discussed. The fragmentation of detected molecular ions of VOCs was found to be quite low, which benefits both qualitative and quantitative determination. The ease of identification and relative simplicity of the mass spectrum is promising for the analysis of VOC mixtures. One of the possible applications of the designed method is the direct determination of VOCs in human exhaled breath for the diagnosis of lung diseases, including lung cancer. However, revealing its potential applicability for this purpose requires further research. ",

keywords = "CRYSTAL MATERIALS, ELEMENTS, FLIGHT MASS-SPECTROMETRY, FLUORINE, GLOW-DISCHARGE, IONIZATION, LUNG-CANCER, PLASMA, POTASSIUM TITANYL PHOSPHATE, QUANTIFICATION",

author = "Чучина, {Виктория Александровна} and Губаль, {Анна Романовна} and Лялькин, {Егор Алексеевич} and Соловьев, {Николай Дмитриевич} and Н.Б. Иваненко and А.А. Ганеев",

year = "2021",

month = may,

doi = "10.46770/AS.2021.031",

language = "English",

volume = "42",

pages = "120--127",

journal = "Atomic Spectroscopy",

issn = "0195-5373",

publisher = "Perkin - Elmer Corp.",

number = "3",

}

RIS

TY - JOUR

T1 - New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

AU - Чучина, Виктория Александровна

AU - Губаль, Анна Романовна

AU - Лялькин, Егор Алексеевич

AU - Соловьев, Николай Дмитриевич

AU - Иваненко, Н.Б.

AU - Ганеев, А.А.

PY - 2021/5

Y1 - 2021/5

N2 - A recent trend in glow discharge analysis, previously considered as a ‘purely inorganic’ technique, is related to the effective ionisation of volatile organic compounds (VOCs). This approach was demonstrated to be capable of analysing VOCs in both model gas mixtures and ambient air. In the current study, the possibility of the direct determination of VOCs of different classes of organic compounds (including toluene, p-xylene, chlorobenzene and 1,2,4-trimethylbenzene) in ambient air using microsecond pulsed glow discharge time-of-flight mass spectrometry (µs-Pulsed GD TOFMS) with copper hollow cathode was demonstrated. The ionisation processes with the formation of molecular ions M +, which can be used for quantification, were discussed. The fragmentation of detected molecular ions of VOCs was found to be quite low, which benefits both qualitative and quantitative determination. The ease of identification and relative simplicity of the mass spectrum is promising for the analysis of VOC mixtures. One of the possible applications of the designed method is the direct determination of VOCs in human exhaled breath for the diagnosis of lung diseases, including lung cancer. However, revealing its potential applicability for this purpose requires further research.

AB - A recent trend in glow discharge analysis, previously considered as a ‘purely inorganic’ technique, is related to the effective ionisation of volatile organic compounds (VOCs). This approach was demonstrated to be capable of analysing VOCs in both model gas mixtures and ambient air. In the current study, the possibility of the direct determination of VOCs of different classes of organic compounds (including toluene, p-xylene, chlorobenzene and 1,2,4-trimethylbenzene) in ambient air using microsecond pulsed glow discharge time-of-flight mass spectrometry (µs-Pulsed GD TOFMS) with copper hollow cathode was demonstrated. The ionisation processes with the formation of molecular ions M +, which can be used for quantification, were discussed. The fragmentation of detected molecular ions of VOCs was found to be quite low, which benefits both qualitative and quantitative determination. The ease of identification and relative simplicity of the mass spectrum is promising for the analysis of VOC mixtures. One of the possible applications of the designed method is the direct determination of VOCs in human exhaled breath for the diagnosis of lung diseases, including lung cancer. However, revealing its potential applicability for this purpose requires further research.

KW - CRYSTAL MATERIALS

KW - ELEMENTS

KW - FLIGHT MASS-SPECTROMETRY

KW - FLUORINE

KW - GLOW-DISCHARGE

KW - IONIZATION

KW - LUNG-CANCER

KW - PLASMA

KW - POTASSIUM TITANYL PHOSPHATE

KW - QUANTIFICATION

UR - http://www.scopus.com/inward/record.url?scp=85107937128&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/037cf3fe-2846-361b-82f5-e811371911ff/

U2 - 10.46770/AS.2021.031

DO - 10.46770/AS.2021.031

M3 - Article

VL - 42

SP - 120

EP - 127

JO - Atomic Spectroscopy

JF - Atomic Spectroscopy

SN - 0195-5373

IS - 3

ER -

ID: 78925670