Standard

New 2-Fluoro 8α-Analogs of Steroidal Estrogens. / Morozkina, S.N.; Fidarov, A.F.; Selivanov, S.I.; Shavva, A.G.

In: Russian Journal of Organic Chemistry, Vol. 50, No. 10, 2014, p. 1520-1526.

Research output: Contribution to journal › Article

Harvard

Morozkina, SN, Fidarov, AF, Selivanov, SI & Shavva, AG 2014, 'New 2-Fluoro 8α-Analogs of Steroidal Estrogens', Russian Journal of Organic Chemistry, vol. 50, no. 10, pp. 1520-1526. https://doi.org/10.1134/S1070428014100182

APA

Morozkina, S. N., Fidarov, A. F., Selivanov, S. I., & Shavva, A. G. (2014). New 2-Fluoro 8α-Analogs of Steroidal Estrogens. Russian Journal of Organic Chemistry, 50(10), 1520-1526. https://doi.org/10.1134/S1070428014100182

Vancouver

Morozkina SN, Fidarov AF, Selivanov SI, Shavva AG. New 2-Fluoro 8α-Analogs of Steroidal Estrogens. Russian Journal of Organic Chemistry. 2014;50(10):1520-1526. https://doi.org/10.1134/S1070428014100182

Author

Morozkina, S.N. ; Fidarov, A.F. ; Selivanov, S.I. ; Shavva, A.G. / New 2-Fluoro 8α-Analogs of Steroidal Estrogens. In: Russian Journal of Organic Chemistry. 2014 ; Vol. 50, No. 10. pp. 1520-1526.

BibTeX

@article{2f799bd1cb314f8db70a7364f5344251,
title = "New 2-Fluoro 8α-Analogs of Steroidal Estrogens",
abstract = "New 8 alpha-analogs of steroidal estrogens containing a fluorine atom in the 2-position have been synthesized with the goal of obtaining modified derivatives with improved biological characteristics. Some of the synthesized compounds have been found to display improved ratio of the osteoprotective and uterotropic effects. 2-Fluoro-16,16-dimethyl-d-homo-8 alpha-estrone and its methyl ether exhibit hypocholesterolemic and cardioprotective activity and no uterotropic effect.",
author = "S.N. Morozkina and A.F. Fidarov and S.I. Selivanov and A.G. Shavva",
year = "2014",
doi = "10.1134/S1070428014100182",
language = "English",
volume = "50",
pages = "1520--1526",
journal = "Russian Journal of Organic Chemistry",
issn = "1070-4280",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "10",

}

RIS

TY - JOUR

T1 - New 2-Fluoro 8α-Analogs of Steroidal Estrogens

AU - Morozkina, S.N.

AU - Fidarov, A.F.

AU - Selivanov, S.I.

AU - Shavva, A.G.

PY - 2014

Y1 - 2014

N2 - New 8 alpha-analogs of steroidal estrogens containing a fluorine atom in the 2-position have been synthesized with the goal of obtaining modified derivatives with improved biological characteristics. Some of the synthesized compounds have been found to display improved ratio of the osteoprotective and uterotropic effects. 2-Fluoro-16,16-dimethyl-d-homo-8 alpha-estrone and its methyl ether exhibit hypocholesterolemic and cardioprotective activity and no uterotropic effect.

AB - New 8 alpha-analogs of steroidal estrogens containing a fluorine atom in the 2-position have been synthesized with the goal of obtaining modified derivatives with improved biological characteristics. Some of the synthesized compounds have been found to display improved ratio of the osteoprotective and uterotropic effects. 2-Fluoro-16,16-dimethyl-d-homo-8 alpha-estrone and its methyl ether exhibit hypocholesterolemic and cardioprotective activity and no uterotropic effect.

U2 - 10.1134/S1070428014100182

DO - 10.1134/S1070428014100182

M3 - Article

VL - 50

SP - 1520

EP - 1526

JO - Russian Journal of Organic Chemistry

JF - Russian Journal of Organic Chemistry

SN - 1070-4280

IS - 10

ER -

ID: 7028970