Research output: Contribution to journal › Article › peer-review
Neurotropic, Psychoactive, and Analgesic Properties of Benzimidazole and Its Derivatives : Physiological Mechanisms. / Cheretaev, I. V.; Korenyuk, I. I.; Nozdrachev, A. D.
In: Neuroscience and Behavioral Physiology, Vol. 48, No. 7, 01.09.2018, p. 848-853.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Neurotropic, Psychoactive, and Analgesic Properties of Benzimidazole and Its Derivatives
T2 - Physiological Mechanisms
AU - Cheretaev, I. V.
AU - Korenyuk, I. I.
AU - Nozdrachev, A. D.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - This review summarizes current data and the results of the authors’ own investigations of the neurotropic, psychoactive, and analgesic properties of benzimidazole and its derivatives. Using a series of compounds of this class as a examples, different aspects of the actions of benzimidazoles on the nervous system of lab animals (mollusks, mice, rats, cats) are considered. The efficacy of benzimidazoles is shown to be due to actions on a number of important physiological mechanisms regulating the functional state of nerve cells and neurotransmitter systems, inflammation processes, and pain.
AB - This review summarizes current data and the results of the authors’ own investigations of the neurotropic, psychoactive, and analgesic properties of benzimidazole and its derivatives. Using a series of compounds of this class as a examples, different aspects of the actions of benzimidazoles on the nervous system of lab animals (mollusks, mice, rats, cats) are considered. The efficacy of benzimidazoles is shown to be due to actions on a number of important physiological mechanisms regulating the functional state of nerve cells and neurotransmitter systems, inflammation processes, and pain.
KW - analgesic effects
KW - benzimidazole
KW - ion channels
KW - neurotropic effects
KW - psychoactive effects
KW - receptors
UR - http://www.scopus.com/inward/record.url?scp=85054489966&partnerID=8YFLogxK
U2 - 10.1007/s11055-018-0639-8
DO - 10.1007/s11055-018-0639-8
M3 - Article
AN - SCOPUS:85054489966
VL - 48
SP - 848
EP - 853
JO - Neuroscience and Behavioral Physiology
JF - Neuroscience and Behavioral Physiology
SN - 0097-0549
IS - 7
ER -
ID: 37013049