Research output: Contribution to journal › Article › peer-review
Neuro-humoral disbalance in chronic heart failure : Classic and modern perspectives. / Obrezan, A. G.; Kulikov, N. V.
In: Russian Journal of Cardiology, Vol. 149, No. 9, 01.01.2017, p. 83-92.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Neuro-humoral disbalance in chronic heart failure
T2 - Classic and modern perspectives
AU - Obrezan, A. G.
AU - Kulikov, N. V.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - In the article, recent data is reviewed, on neuro-humorall disbalance in chronic heart failure, including compensatory hyperactivation of sympathetic system, reninangiotensin-aldosterone system, endothelial system, endopeptides, and decrease of efficacy of the system of natriuretic peptides (atrial natriuretic peptide, brain natriuretic peptide, endothelial natriuretic peptide). In the review, it is shown that chronic heart failure as clinical syndrome is characterized by close interaction of hemodynamical dysfunction of myocardium and compensatory neuro-humoral mechanisms. All neuro-humoral mechanisms closely bound together acting in compensation of chronic heart failure progression, and many of them show compensatory role, as pathologic.
AB - In the article, recent data is reviewed, on neuro-humorall disbalance in chronic heart failure, including compensatory hyperactivation of sympathetic system, reninangiotensin-aldosterone system, endothelial system, endopeptides, and decrease of efficacy of the system of natriuretic peptides (atrial natriuretic peptide, brain natriuretic peptide, endothelial natriuretic peptide). In the review, it is shown that chronic heart failure as clinical syndrome is characterized by close interaction of hemodynamical dysfunction of myocardium and compensatory neuro-humoral mechanisms. All neuro-humoral mechanisms closely bound together acting in compensation of chronic heart failure progression, and many of them show compensatory role, as pathologic.
KW - Chronic heart failure
KW - Neuro-humoral disbalance
KW - Neuro-humoral mechanisms
UR - http://www.scopus.com/inward/record.url?scp=85032869160&partnerID=8YFLogxK
U2 - 10.15829/1560-4071-2017-9-83-92
DO - 10.15829/1560-4071-2017-9-83-92
M3 - Article
AN - SCOPUS:85032869160
VL - 149
SP - 83
EP - 92
JO - РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ
JF - РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ
SN - 1560-4071
IS - 9
ER -
ID: 53264476