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Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys. / Rozanov, V. A.

In: Ukrainskii biokhimicheskii zhurnal, Vol. 59, No. 5, 01.09.1987, p. 41-45.

Research output: Contribution to journal › Article › peer-review

Harvard

Rozanov, VA 1987, 'Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys.', Ukrainskii biokhimicheskii zhurnal, vol. 59, no. 5, pp. 41-45.

APA

Rozanov, V. A. (1987). Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys. Ukrainskii biokhimicheskii zhurnal, 59(5), 41-45.

Vancouver

Rozanov VA. Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys. Ukrainskii biokhimicheskii zhurnal. 1987 Sep 1;59(5):41-45.

Author

Rozanov, V. A. / Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys. In: Ukrainskii biokhimicheskii zhurnal. 1987 ; Vol. 59, No. 5. pp. 41-45.

BibTeX

@article{c3e46998ee464abbbb5868c955a60d47,
title = "Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys.",
abstract = "The glutamate decarboxylase activity in rough homogenates of cerebellum, cortex and truncal part of the rat brain was studied under different conditions of incubation: in the presence of 25 mM glutamate sodium, 0.4 mM pyridoxal-5'-phosphate and both these components. It is found that the initial glutamate decarboxylase activity in cerebellum homogenates is approximately twice as high as in the cortex and trunk homogenates. Addition of the substrate and cofactor, especially in the combination, stimulates considerably the yield of gamma-aminobutyric acid (GABA) in the glutamate decarboxylase reaction, the most pronounced activation being observed in the truncal homogenates. The glutamate/GABA relation both initial and after the completion of the reaction is the maximal in the cortex and minimal in the truncal part of the brain. The data obtained evidence for the differences in the content of the GABA-producing enzyme rather than for the presence of the specific mechanisms of the enzyme regulation in different brain areas.",
author = "Rozanov, {V. A.}",
year = "1987",
month = sep,
day = "1",
language = "русский",
volume = "59",
pages = "41--45",
journal = "Ukrainian biochemical journal",
issn = "2409-4943",
publisher = "Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine (NASU)",
number = "5",

}

RIS

TY - JOUR

T1 - Nekotorye osobennosti glutamatdekarboksilaznoǐ reaktsii v gomogenatakh razlichnykh otdelov golovnogo mozga krys.

AU - Rozanov, V. A.

PY - 1987/9/1

Y1 - 1987/9/1

N2 - The glutamate decarboxylase activity in rough homogenates of cerebellum, cortex and truncal part of the rat brain was studied under different conditions of incubation: in the presence of 25 mM glutamate sodium, 0.4 mM pyridoxal-5'-phosphate and both these components. It is found that the initial glutamate decarboxylase activity in cerebellum homogenates is approximately twice as high as in the cortex and trunk homogenates. Addition of the substrate and cofactor, especially in the combination, stimulates considerably the yield of gamma-aminobutyric acid (GABA) in the glutamate decarboxylase reaction, the most pronounced activation being observed in the truncal homogenates. The glutamate/GABA relation both initial and after the completion of the reaction is the maximal in the cortex and minimal in the truncal part of the brain. The data obtained evidence for the differences in the content of the GABA-producing enzyme rather than for the presence of the specific mechanisms of the enzyme regulation in different brain areas.

AB - The glutamate decarboxylase activity in rough homogenates of cerebellum, cortex and truncal part of the rat brain was studied under different conditions of incubation: in the presence of 25 mM glutamate sodium, 0.4 mM pyridoxal-5'-phosphate and both these components. It is found that the initial glutamate decarboxylase activity in cerebellum homogenates is approximately twice as high as in the cortex and trunk homogenates. Addition of the substrate and cofactor, especially in the combination, stimulates considerably the yield of gamma-aminobutyric acid (GABA) in the glutamate decarboxylase reaction, the most pronounced activation being observed in the truncal homogenates. The glutamate/GABA relation both initial and after the completion of the reaction is the maximal in the cortex and minimal in the truncal part of the brain. The data obtained evidence for the differences in the content of the GABA-producing enzyme rather than for the presence of the specific mechanisms of the enzyme regulation in different brain areas.

UR - http://www.scopus.com/inward/record.url?scp=0023409063&partnerID=8YFLogxK

M3 - статья

C2 - 3686692

AN - SCOPUS:0023409063

VL - 59

SP - 41

EP - 45

JO - Ukrainian biochemical journal

JF - Ukrainian biochemical journal

SN - 2409-4943

IS - 5

ER -

ID: 42771104