Research output: Contribution to journal › Review article › peer-review
Natural Polymers, Their Modifications and Composites with Synthetic Polymers for Tympanic Membrane Regeneration. / Shaikenov, Roman O.; Serbun, Polina G.; Zhang, Jingran; Wu, Hao; Wang, Zuobin; Snetkov, Petr P.; Morozkina, Svetlana N.
In: Journal of Functional Biomaterials, Vol. 16, No. 10, 13.10.2025, p. 384-390.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - Natural Polymers, Their Modifications and Composites with Synthetic Polymers for Tympanic Membrane Regeneration
AU - Shaikenov, Roman O.
AU - Serbun, Polina G.
AU - Zhang, Jingran
AU - Wu, Hao
AU - Wang, Zuobin
AU - Snetkov, Petr P.
AU - Morozkina, Svetlana N.
PY - 2025/10/13
Y1 - 2025/10/13
N2 - The perforation of the tympanic membrane is a world-wide clinical problem resulting from trauma or infection and requiring effective regeneration methods. In recent years researchers have focused on natural polymers as promising materials for restoring the structure and function of the tympanic membrane. This review summarizes current advances in the use of natural polymers, such as silk fibroin, chitosan, hyaluronic acid, collagen, bacterial cellulose, alginates and others, for the treatment of tympanic membrane perforations. The key properties of these materials are discussed, including their biocompatibility, biodegradability, mechanical strength, and ability to support cell adhesion and proliferation. The review also covers the potential of natural polymers and their combinations in tympanic membrane regeneration and suggests the directions for future research.
AB - The perforation of the tympanic membrane is a world-wide clinical problem resulting from trauma or infection and requiring effective regeneration methods. In recent years researchers have focused on natural polymers as promising materials for restoring the structure and function of the tympanic membrane. This review summarizes current advances in the use of natural polymers, such as silk fibroin, chitosan, hyaluronic acid, collagen, bacterial cellulose, alginates and others, for the treatment of tympanic membrane perforations. The key properties of these materials are discussed, including their biocompatibility, biodegradability, mechanical strength, and ability to support cell adhesion and proliferation. The review also covers the potential of natural polymers and their combinations in tympanic membrane regeneration and suggests the directions for future research.
KW - bacterial cellulose
KW - biocompatible composites
KW - collagen
KW - eardrum
KW - hyaluronic acid
KW - natural polymers
KW - silk fibroin
KW - tympanic membrane
UR - https://www.mendeley.com/catalogue/e4ec5ee4-6584-3353-8230-f04de1585c77/
U2 - 10.3390/jfb16100384
DO - 10.3390/jfb16100384
M3 - Review article
C2 - 41149730
VL - 16
SP - 384
EP - 390
JO - Journal of Functional Biomaterials
JF - Journal of Functional Biomaterials
SN - 2079-4983
IS - 10
ER -
ID: 144719426