Nash opyt primeneniia otechestvennogo preparata legochnogo surfaktanta dlia lecheniia sindroma ostrogo povrezhdeniia legkikh i tiazhelykh pnevmonii u detei. / Tsybul'kin, E. K.; Rozenberg, O. A.; Seiliev, A. A.; Volchkov, V. A.; Zaitseva, N. V.; Kuz'menko, I. G.; Loshakova, L. V.; Pelogievskaia, Z. I.; Portniagin, I. V.; Shefer, S. P.
In: Anesteziologiia i reanimatologiia, No. 2, 03.1999, p. 61-65.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Nash opyt primeneniia otechestvennogo preparata legochnogo surfaktanta dlia lecheniia sindroma ostrogo povrezhdeniia legkikh i tiazhelykh pnevmonii u detei.
AU - Tsybul'kin, E. K.
AU - Rozenberg, O. A.
AU - Seiliev, A. A.
AU - Volchkov, V. A.
AU - Zaitseva, N. V.
AU - Kuz'menko, I. G.
AU - Loshakova, L. V.
AU - Pelogievskaia, Z. I.
AU - Portniagin, I. V.
AU - Shefer, S. P.
PY - 1999/3
Y1 - 1999/3
N2 - Six critical patients aged 2 months to 13 years with lung diseases were treated by pulmonary surfactant preparation. Three of these children developed the acute respiratory distress syndrome in the presence of grave pneumonia (1 case), asphyxial drowing (1 case), and small-small intestinal invagination (1 case), three others developed acute bilateral large focal pneumonia with or without repeated atelectases. The drug Surfactant-BL was administered in a dose of 400 micrograms/m2 by instillations (2 cases) or by inhalation aerosols. The drug improved blood gases, lung compliance, x-ray picture, and clinical status of all patients, permitting a decrease in IMV/SIMV parameters within 12-48 h after the last administration and discontinuation of IMV/SIMV in 3 patients within 24 h after 1 or two administrations. Five children survived, 1 (with asphyxial drowning) died with brain edema and wedging syndrome. Surfactant-BL is a safe and effective drug; administration through alveolar nebulisers should be preferred.
AB - Six critical patients aged 2 months to 13 years with lung diseases were treated by pulmonary surfactant preparation. Three of these children developed the acute respiratory distress syndrome in the presence of grave pneumonia (1 case), asphyxial drowing (1 case), and small-small intestinal invagination (1 case), three others developed acute bilateral large focal pneumonia with or without repeated atelectases. The drug Surfactant-BL was administered in a dose of 400 micrograms/m2 by instillations (2 cases) or by inhalation aerosols. The drug improved blood gases, lung compliance, x-ray picture, and clinical status of all patients, permitting a decrease in IMV/SIMV parameters within 12-48 h after the last administration and discontinuation of IMV/SIMV in 3 patients within 24 h after 1 or two administrations. Five children survived, 1 (with asphyxial drowning) died with brain edema and wedging syndrome. Surfactant-BL is a safe and effective drug; administration through alveolar nebulisers should be preferred.
UR - http://www.scopus.com/inward/record.url?scp=0033090091&partnerID=8YFLogxK
M3 - статья
C2 - 10360078
AN - SCOPUS:0033090091
SP - 61
EP - 65
JO - Russian Journal of Anesthesiology and Reanimatology /Anesteziologiya i Reanimatologiya
JF - Russian Journal of Anesthesiology and Reanimatology /Anesteziologiya i Reanimatologiya
SN - 0201-7563
IS - 2
ER -
ID: 85030874