Research output: Contribution to journal › Article › peer-review
Mouse models ARDS of viral etiology (influenza): the possibility of dynamic intravital assessment of lung tissue using computed tomography. / Соколович, Евгений Георгиевич; Яблонский, Петр Казимирович; Виноградова, Татьяна Ивановна; Азаров, Артем; Пичкур, Лолита.
In: European Respiratory Journal, Supplement, Vol. 58, No. S65, 05.09.2021, p. 3172.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Mouse models ARDS of viral etiology (influenza): the possibility of dynamic intravital assessment of lung tissue using computed tomography
AU - Соколович, Евгений Георгиевич
AU - Яблонский, Петр Казимирович
AU - Виноградова, Татьяна Ивановна
AU - Азаров, Артем
AU - Пичкур, Лолита
N1 - Mouse models ARDS of viral etiology (influenza): the possibility of dynamic intravital assessment of lung tissue using computed tomography / P. Gavrilov, A. Azarov, L. Pichkur, T. Vinogradova, E. Sokolovich, P. Yаblonskiy // European Respiratory Journal, 2021. V. 58. – P.3172
PY - 2021/9/5
Y1 - 2021/9/5
N2 - The aim of the study was to investigate the intravital lung parenchyma lesions follow-up in severe forms of experimental influenza infection by CT. An experimental study was carried out on 40 male C57black/6 mice weighing 16-18 g. Animals were divided into two groups: 1) uninfected mice - n = 10; 2) infected mice - n = 30 (infected intranasally with influenza virus A/PuertoRico/8/34 (H1N1), infectious dose 4.4 lg TID50/animal). The severity of infection was assessed according to the following criteria: daily control of the animals’ body weight; intravital lungs CT; lungs biometric and morphological examination. CT was performed in 5 randomly selected animals from the infection group at the first, third and fifth day after infection.
AB - The aim of the study was to investigate the intravital lung parenchyma lesions follow-up in severe forms of experimental influenza infection by CT. An experimental study was carried out on 40 male C57black/6 mice weighing 16-18 g. Animals were divided into two groups: 1) uninfected mice - n = 10; 2) infected mice - n = 30 (infected intranasally with influenza virus A/PuertoRico/8/34 (H1N1), infectious dose 4.4 lg TID50/animal). The severity of infection was assessed according to the following criteria: daily control of the animals’ body weight; intravital lungs CT; lungs biometric and morphological examination. CT was performed in 5 randomly selected animals from the infection group at the first, third and fifth day after infection.
KW - Animal modelsVirusesARDS (Acute Respiratory Distress Syndrome)
UR - https://www.elibrary.ru/item.asp?id=47269791
U2 - https://erj.ersjournals.com/content/58/suppl_65/PA3172
DO - https://erj.ersjournals.com/content/58/suppl_65/PA3172
M3 - Article
VL - 58
SP - 3172
JO - European Respiratory Journal, Supplement
JF - European Respiratory Journal, Supplement
SN - 0904-1850
IS - S65
T2 - ERS International Congress 2021
Y2 - 5 September 2021 through 8 September 2021
ER -
ID: 98259084