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Molecular psychiatry of zebrafish. / Stewart, A. M.; Ullmann, J. F.P.; Norton, W. H.J.; Parker, M. O.; Brennan, C. H.; Gerlai, R.; Kalueff, A. V.

In: Molecular Psychiatry, Vol. 20, No. 1, 05.02.2015, p. 2-17.

Research output: Contribution to journal › Review article › peer-review

Harvard

Stewart, AM, Ullmann, JFP, Norton, WHJ, Parker, MO, Brennan, CH, Gerlai, R & Kalueff, AV 2015, 'Molecular psychiatry of zebrafish', Molecular Psychiatry, vol. 20, no. 1, pp. 2-17. https://doi.org/10.1038/mp.2014.128

APA

Stewart, A. M., Ullmann, J. F. P., Norton, W. H. J., Parker, M. O., Brennan, C. H., Gerlai, R., & Kalueff, A. V. (2015). Molecular psychiatry of zebrafish. Molecular Psychiatry, 20(1), 2-17. https://doi.org/10.1038/mp.2014.128

Vancouver

Stewart AM, Ullmann JFP, Norton WHJ, Parker MO, Brennan CH, Gerlai R et al. Molecular psychiatry of zebrafish. Molecular Psychiatry. 2015 Feb 5;20(1):2-17. https://doi.org/10.1038/mp.2014.128

Author

Stewart, A. M. ; Ullmann, J. F.P. ; Norton, W. H.J. ; Parker, M. O. ; Brennan, C. H. ; Gerlai, R. ; Kalueff, A. V. / Molecular psychiatry of zebrafish. In: Molecular Psychiatry. 2015 ; Vol. 20, No. 1. pp. 2-17.

BibTeX

@article{8a91a971fd5f4c7c89d371127154cab6,

title = "Molecular psychiatry of zebrafish",

abstract = "Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry. Here, we discuss the molecular psychiatry of zebrafish, and its implications for translational neuroscience research and modeling central nervous system (CNS) disorders. In particular, we outline recent genetic and technological developments allowing for in vivo examinations, high-throughput screening and whole-brain analyses in larval and adult zebrafish. We also summarize the application of these molecular techniques to the understanding of neuropsychiatric disease, outlining the potential of zebrafish for modeling complex brain disorders, including attention-deficit/hyperactivity disorder (ADHD), aggression, post-traumatic stress and substance abuse. Critically evaluating the advantages and limitations of larval and adult fish tests, we suggest that zebrafish models become a rapidly emerging new field in modern molecular psychiatry research.",

author = "Stewart, {A. M.} and Ullmann, {J. F.P.} and Norton, {W. H.J.} and Parker, {M. O.} and Brennan, {C. H.} and R. Gerlai and Kalueff, {A. V.}",

year = "2015",

month = feb,

day = "5",

doi = "10.1038/mp.2014.128",

language = "English",

volume = "20",

pages = "2--17",

journal = "Molecular Psychiatry",

issn = "1359-4184",

publisher = "Nature Publishing Group",

number = "1",

}

RIS

TY - JOUR

T1 - Molecular psychiatry of zebrafish

AU - Stewart, A. M.

AU - Ullmann, J. F.P.

AU - Norton, W. H.J.

AU - Parker, M. O.

AU - Brennan, C. H.

AU - Gerlai, R.

AU - Kalueff, A. V.

PY - 2015/2/5

Y1 - 2015/2/5

N2 - Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry. Here, we discuss the molecular psychiatry of zebrafish, and its implications for translational neuroscience research and modeling central nervous system (CNS) disorders. In particular, we outline recent genetic and technological developments allowing for in vivo examinations, high-throughput screening and whole-brain analyses in larval and adult zebrafish. We also summarize the application of these molecular techniques to the understanding of neuropsychiatric disease, outlining the potential of zebrafish for modeling complex brain disorders, including attention-deficit/hyperactivity disorder (ADHD), aggression, post-traumatic stress and substance abuse. Critically evaluating the advantages and limitations of larval and adult fish tests, we suggest that zebrafish models become a rapidly emerging new field in modern molecular psychiatry research.

AB - Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry. Here, we discuss the molecular psychiatry of zebrafish, and its implications for translational neuroscience research and modeling central nervous system (CNS) disorders. In particular, we outline recent genetic and technological developments allowing for in vivo examinations, high-throughput screening and whole-brain analyses in larval and adult zebrafish. We also summarize the application of these molecular techniques to the understanding of neuropsychiatric disease, outlining the potential of zebrafish for modeling complex brain disorders, including attention-deficit/hyperactivity disorder (ADHD), aggression, post-traumatic stress and substance abuse. Critically evaluating the advantages and limitations of larval and adult fish tests, we suggest that zebrafish models become a rapidly emerging new field in modern molecular psychiatry research.

UR - http://www.scopus.com/inward/record.url?scp=84908351502&partnerID=8YFLogxK

U2 - 10.1038/mp.2014.128

DO - 10.1038/mp.2014.128

M3 - Review article

C2 - 25349164

AN - SCOPUS:84908351502

VL - 20

SP - 2

EP - 17

JO - Molecular Psychiatry

JF - Molecular Psychiatry

SN - 1359-4184

IS - 1

ER -

ID: 97904591